切换至 "中华医学电子期刊资源库"

中华肥胖与代谢病电子杂志 ›› 2017, Vol. 03 ›› Issue (01) : 19 -24. doi: 10.3877/cma.j.issn.2095-9605.2017.01.004

所属专题: 机器人手术 文献

临床研究

达芬奇机器人辅助Roux-en-Y胃旁路术在肥胖症治疗中的应用价值
夏泽锋1, 王清波1, 帅晓明1, 高金波1, 蔡明1, 汪赓1, 胡超杰1, 李桉树1, 杜锦鹏1, 赵宁1, 王国斌1, 陶凯雄1,()   
  1. 1. 430022 武汉,华中科技大学同济医学院附属协和医院胃肠外科
  • 收稿日期:2016-12-15 出版日期:2017-02-28
  • 通信作者: 陶凯雄
  • 基金资助:
    国家自然科学基金(81200276); 湖北省自然科学基金(2015CFB710); 湖北省卫生和计划生育科研项目青年基金(WJ2015Q001); 华中科技大学附属协和医院科研基金(000003396)

Application value of Da Vinci robot-assisted Roux-en-Y gastric bypass in treating obesity

Zefeng Xia1, Qingbo Wang1, Xiaoming Shuai1, Jinbo Gao1, Ming Cai1, Geng Wang1, Chaojie Hu1, Anshu Li1, Jinpeng Du1, Ning Zhao1, Guobin Wang1, Kaixiong Tao1,()   

  1. 1. Department of Gastrointestinal Surgery, Xiehe Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2016-12-15 Published:2017-02-28
  • Corresponding author: Kaixiong Tao
  • About author:
    Corresponding author: Tao Kaixiong, Email:
引用本文:

夏泽锋, 王清波, 帅晓明, 高金波, 蔡明, 汪赓, 胡超杰, 李桉树, 杜锦鹏, 赵宁, 王国斌, 陶凯雄. 达芬奇机器人辅助Roux-en-Y胃旁路术在肥胖症治疗中的应用价值[J/OL]. 中华肥胖与代谢病电子杂志, 2017, 03(01): 19-24.

Zefeng Xia, Qingbo Wang, Xiaoming Shuai, Jinbo Gao, Ming Cai, Geng Wang, Chaojie Hu, Anshu Li, Jinpeng Du, Ning Zhao, Guobin Wang, Kaixiong Tao. Application value of Da Vinci robot-assisted Roux-en-Y gastric bypass in treating obesity[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2017, 03(01): 19-24.

目的

探讨达芬奇机器人辅助Roux-en-Y胃旁路术(RRYGB)在肥胖症治疗中的应用价值。

方法

回顾性分析2012年7月至2016年11月在华中科技大学同济医学院附属协和医院胃肠外科接受代谢手术治疗的9例肥胖症患者的临床资料。所有患者均签署知情同意书,符合医学伦理学规定。根据是否接受机器人辅助治疗,患者被分为RRYGB组和腹腔镜Roux-en-Y胃旁路术(LRYGB)组。其中RRYGB组3例,男1例,女2例;年龄(37±7)岁。LRYGB组6例,男3例,女3例;年龄(31±7)岁。比较两组患者的手术时间、术中出血量、术后通气时间、术后住院时间,术前和术后1个月的体质量、体质指数(BMI)、空腹血糖(FPG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯(TG)和总胆固醇(TC)水平。两组临床指标的比较采用独立样本t检验或χ2检验。

结果

所有患者均成功完成手术治疗。RRYGB组患者的术中出血量为(46±7)ml,明显少于LRYGB组的(82±6)ml(t= –8.03,P<0.05)。术后1个月,RRYGB和LRYGB组患者的BMI水平分别为(34±5)和(35±4)kg/m2,均明显低于术前的(39±7)和(40±5)kg/m2t=5.33、7.33,P<0.05),两组患者的BMI减少量比较差异无统计学意义(t=0.35,P>0.05)。

结论

RRYGB治疗肥胖症的短期效果良好,但由于本研究纳入例数过少,随访时间不足,故其安全性和有效性有待于进一步研究以明确。

Objective

To investigate the clinical application value of robot-assisted Roux-en-Y gastric bypass (RRYGB) in treating obesity.

Methods

Clinical data of 9 obese patients undergoing bariatric surgery in Xiehe Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology from July 2012 to November 2016 were retrospectively studied. The informed consents of all patients were obtained and the local ethical committee approval had been received. According to whether RRYGB was carried out or not, these patients were divided into the RRYGB group and the laparoscopic Roux-en-Y gastric bypass (LRYGB) group. Three patients were included into the RRYGB group, of whom 1 was male and 2 were females with an average age of (37±7) years old. Six patients were included into the LRYGB group, of whom 3 were males and 3 were females with an average age of (31±7) years old. Operation time, intraoperative blood loss, postoperative ventilation time, postoperative hospital stay; and body weight, body mass index (BMI), fasting plasma glucose (FPG), low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride (TG) and total cholesterol (TC) before and 1 month after operation were compared between the two groups. Comparisons of these data between the two groups were conducted using t test or χ2 test.

Results

All the patients received bariatric surgery successfully. Intraoperative blood loss of the RRYGB group was (46±7) ml, which was significantly lower than (82±6) ml of the LRYGB group (t= –8.03, P<0.05). One month after operation, BMI of the RRYGB and LRYGB groups were (34±5) and (35±4) kg/m2 respectively, which were significantly lower than (39±7) and (40±5) kg/m2 before operation (t=5.33, 7.33, P<0.05); and there is no statistical difference in BMI reduction between the two groups.

Conclusions

RRYGB is a therapeutic method with a good short-term effect on obesity, but its safety and effectiveness remain to be further investigated because the number of patients was too small and the fellow-up time was not long enough in this research.

图1 RRYGB机器站位。1A为RRYGB 3臂法器械站位;1B为RRYGB 4臂法器械站位(图片来自于"Intuitive Surgical,Da Vinci Gastric Bypass")
图2 RRYGB器械孔位置。2A为RRYGB 3臂法器械孔位置;2B为RRYGB 4臂法器械孔位置(图片来自于"Intuitive Surgical,Da Vinci Gastric Bypass")
图3 LRYGB 5孔法的Trocar孔位置
图4 LRYGB操作原理示意图
表1 RRYGB组和LRYGB组肥胖症患者术前一般资料比较(±s
表2 RRYGB组和LRYGB组肥胖症患者围手术期临床指标比较(±s
表3 RRYGB组和LRYGB组肥胖症患者术后1个月临床指标比较(±s
[1]
王存川,沈莹莹,杨景哥. 腹腔镜Roux-en-Y胃旁路手术治疗肥胖症[J]. 腹腔镜外科杂志, 2011, 16(4):243-246.
[2]
中国医师协会外科医师分会肥胖和糖尿病外科医师委员会. 中国肥胖和2型糖尿病外科治疗指南(2014)[J]. 中国实用外科学杂志, 2014, 34(11):1005-1010.
[3]
Mason EE, Ito C. Gastric bypass in obesity[J]. Surg Clin North Am, 1967, 47(6):1345-1351.
[4]
Mingrone G, Panunzi S, De Gaetano A, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes[J]. N Engl J Med, 2012, 366(17):1577-1585.
[5]
Li JF, Lai DD, Ni B, et al. Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials[J]. Can J Surg, 2013, 56(6):E158-E164.
[6]
Helmiö M, Victorzon M, Ovaska J, et al. SLEEVEPASS: a randomized prospective multicenter study comparing laparoscopic sleevegastrectomy and gastric bypass in the treatment of morbid obesity:preliminary results[J]. Surg Endosc, 2012, 26(9):2521-2526.
[7]
Ramón JM, Salvans S, Crous X, et al. Effect of Roux-en-Y gastric bypass vs sleeve gastrectomy on glucose and gut hormones: a prospective randomised trial[J]. J Gastrointest Surg, 2012, 16(6):1116-1122.
[8]
Wittgrove AC, Clark GW, Tremblay LJ. Laparoscopic gastric bypass, Roux-en-Y: preliminary report of five cases[J]. Obes Surg, 1994, 4(4):353-357.
[9]
Kehagias I, Karamanakos SN, Argentou M, et al. Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI<50 kg/m2[J]. Obes Surg, 2011, 21(11):1650-1656.
[10]
刘金鸽,张立超,马利锋, 等. 腹腔镜袖状胃切除术在治疗病态肥胖症中的应用价值[J]. 中华肥胖与代谢病电子杂志, 2016, 2(1):17-21.
[11]
Markar SR, Karthikesalingam AP, Venkat-Ramen V, et al. Robotic vs laparoscopic Roux-en-Y gastric bypass in morbidly obese patients: systematic review and pooled analysis[J]. Int J Med Robot, 2011, 7(4):393-400.
[12]
Nguyen NT, Slone JA, Nguyen XM, et al. A prospective randomized trial of laparoscopic gastric bypass versus laparoscopic adjustable gastric banding for the treatment of morbid obesity: Outcomes, quality of life, and costs[J]. Ann Surg, 2009, 250(4):631-641.
[13]
Vilallonga R, Fort JM, Gonzalez O, et al. The initial learning curve for robot-assisted sleeve gastrectomy: a surgeon’s experience while introducing the robotic technology in a bariatric surgery department[J]. Minim Invasive Surg, 2012(2012):347131.
[14]
Rezvani M, Sucandy I, Antanavicius G. Totally robotic stapleless vertical sleeve gastrectomy[J]. Surg Obes Relat Dis, 2013, 9(5):e79-e81.
[15]
Buchs NC, Pugin F, Bucher P, et al. Learning curve for robot-assisted Roux-en-Y gastric bypass[J]. Surg Endosc, 2012, 26(4):1116-1121.
[1] 向韵, 卢游, 杨凡. 全氟及多氟烷基化合物暴露与儿童肥胖症相关性研究现状[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(05): 569-574.
[2] 陈嘉婷, 杜美君, 石冰, 黄汉尧. 母体系统性疾病对新生儿唇腭裂发生的影响[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(04): 262-268.
[3] 吉顺富, 汤晓燕, 徐进. 腹腔镜近端胃癌根治术中拓展胃后间隙在肥胖患者中的应用研究[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(04): 393-396.
[4] 杨波, 胡旭, 何金艳, 谢铭. 腹腔镜袖状胃切除术管胃固定研究现状[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(04): 452-455.
[5] 颜帅, 胡旭, 苟晓梅, 谢铭. 腹腔镜胃袖状切除术后并发症处置策略[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(02): 220-224.
[6] 刘盾, 潘晟. 不同入路腹腔镜袖状胃切除术用于肥胖症合并2型糖尿病的效果[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(02): 150-154.
[7] 玉素江·图荪托合提, 韩琦, 麦麦提艾力·麦麦提明, 黄旭东, 王浩, 克力木·阿不都热依木, 艾克拜尔·艾力. 腹腔镜袖状胃切除或联合食管裂孔疝修补术对肥胖症合并胃食管反流病的中期疗效分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(05): 501-506.
[8] 刘见, 杨晓波, 何均健, 等. 应用电钩三孔法腹腔镜袖状胃切除术[J/OL]. 中华腔镜外科杂志(电子版), 2024, 17(06): 363-364.
[9] 中国医师协会外科医师分会肥胖代谢病综合管理与护理专家工作组, 中国医师协会外科医师分会肥胖和代谢病外科专家工作组, 中国肥胖代谢外科研究协作组. 肥胖代谢外科医学科普中国专家共识(2024 版)[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(04): 227-234.
[10] 中国医师协会外科医师分会肥胖和代谢病外科专家工作组, 中国医师协会外科医师分会胃食管反流疾病诊疗外科专家工作组, 日本肥胖治疗学会, 韩国减重与代谢外科学会. 袖状胃切除术患者胃食管反流病诊治专家共识(2024版)[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(03): 145-162.
[11] 颜宥彤, 赵锐, 万谦益, 张贵祥, 沈弘毅, 程中, 陈亿. GLP-1受体激动剂——司美格鲁肽的应用及安全性[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(02): 88-93.
[12] 崔磊, 徐东升. 减重手术治疗肥胖患者胰岛素抵抗的研究进展[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(02): 127-132.
[13] 邢颖, 闫文貌. 单孔腹腔镜袖状胃切除术发展现状[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(02): 133-137.
[14] 中国医师协会外科医师分会肥胖和糖尿病外科专家工作组. 减重手术相关贫血管理策略中国专家共识(2024版)[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(01): 1-8.
[15] 谭莺, 雷普润, 莫子健, 陈图锋, 陈燕铭. 减重代谢手术在糖胖病治疗中的应用及效果分析[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(01): 9-14.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?