To study the therapeutic effect of microwave ablation and total endoscopic thyroidectomy in the treatment of benign thyroid nodular disease in overweight patients.

I120 patients who were diagnosed as benign unilateral thyroid nodul and treated in our hospital from May 2017 and May 2018 were randomly divides into total endoscopic thyroidectom group and microwave ablation group, body mass index (BMI) of all patients≥24 kg/m². The total endoscopic thyroidectom group (45 cases) were treated with total endoscopic thyroidectom and the microwave ablation group (75 cases) were treated with microwave ablation, and then compared the efficacy.

The operation time and the length of hospital stay of the microwave ablation group is lower than that of the therapy of the total endoscopic thyroidectom group, with lower blood loss and incidence of postoperative complications (P<0.05). Compared with the total endoscopic thyroidectom group, microwave ablation has less postoperative pain and less effect of thyroid function, with higher cosmetic score (P<0.05) . Finally, after 12 months of regular follow-up of microwave ablation group, the decreasing rate of thyroid nodule is 43.7% and the shrinking rate of the volume of thyroid nodule is up to 87.9%, showing obvious therapeutic effect.

Microwave ablation for the treatment of patients with overweight thyroid nodules has the advantages of minimally invasive, less invasive, and high safety. It can significantly reduce postoperative pain and improve cosmetic evaluation, and can avoid affecting the thyroid function of patients. It is worthy of clinical application.