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中华肥胖与代谢病电子杂志 ›› 2025, Vol. 11 ›› Issue (01) : 26 -32. doi: 10.3877/cma.j.issn.2095-9605.2025.01.004

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替西帕肽在优化减重代谢手术中的作用展望
李梦蝶1, 王勇1,()   
  1. 1. 110001 沈阳,中国医科大学附属第四医院普通外科
  • 收稿日期:2025-01-08 出版日期:2025-02-28
  • 通信作者: 王勇

Prospects of Tirzepatide in optimizing metabolic and bariatric surgery

Mengdie Li1, Yong Wang1,()   

  1. 1. Department of General Surgery,The Fourth Affiliated Hospital of China Medical University,Shenyang 110001,China
  • Received:2025-01-08 Published:2025-02-28
  • Corresponding author: Yong Wang
引用本文:

李梦蝶, 王勇. 替西帕肽在优化减重代谢手术中的作用展望[J/OL]. 中华肥胖与代谢病电子杂志, 2025, 11(01): 26-32.

Mengdie Li, Yong Wang. Prospects of Tirzepatide in optimizing metabolic and bariatric surgery[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2025, 11(01): 26-32.

肥胖症及相关代谢疾病已成为全球性健康挑战,减重代谢手术是目前治疗肥胖症及2型糖尿病最有效的手段之一。近年来,随着对减重代谢手术机制的深入探索,提出了越来越多的辅助治疗手段以优化手术效果,替西帕肽作为一种治疗2型糖尿病的新型药物,因其在改善体重管理和控制糖尿病方面的卓越效果,引起了广泛关注。本文综述了替西帕肽和减重代谢手术在体重减轻上的疗效及安全性,以及替西帕肽在减重代谢手术中的潜在应用,探讨其在手术前后的作用,并展望未来研究方向,以期为临床治疗提供新的思路和策略。

Obesity and related metabolic diseases have become a global health challenge,Metabolic and bariatric surgery is currently one of the most effective treatments for obesity and type 2 diabetes.In recent years,with the deeper understanding of the mechanisms of metabolic surgery,more and more adjunctive therapies have been proposed to optimize the surgical outcome.Tirzepatide,a novel drug for the treatment of type 2 diabetes mellitus,has attracted widespread attention because of its excellent results in improving weight management and diabetes control.This article reviews the efficacy and safety of Tirzepatide and metabolic surgery in weight loss,as well as the potential application of Tirzepatide in metabolic surgery,discusses its role before and after surgery,and looks forward to future research directions,with the aim of providing new ideas and strategies for clinical treatment.

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