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中华肥胖与代谢病电子杂志 ›› 2025, Vol. 11 ›› Issue (01) : 1 -10. doi: 10.3877/cma.j.issn.2095-9605.2025.01.001

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中国肥胖代谢外科临床研究现状及展望:一项计量学研究
张睿旻1, 朱红梅1, 刘雁军1,()   
  1. 1. 610031 成都,西南交通大学医学院·成都市第三人民医院(西南交通大学附属医院)普外科
  • 收稿日期:2025-01-07 出版日期:2025-02-28
  • 通信作者: 刘雁军
  • 基金资助:
    西部减重代谢手术患者队列研究(ChiCTR2300073353)

Current status and prospects of clinical research on metabolic and bariatric surgery in China

Ruimin Zhang1, Hongmei Zhu1, Yanjun Liu1,()   

  1. 1. Department of General Surgery,The Third People's Hospital of Chengdu(Affiliated Hospital of Southwest Jiaotong University),College of Medicine,Southwest Jiaotong University,Chengdu 610031,China
  • Received:2025-01-07 Published:2025-02-28
  • Corresponding author: Yanjun Liu
引用本文:

张睿旻, 朱红梅, 刘雁军. 中国肥胖代谢外科临床研究现状及展望:一项计量学研究[J/OL]. 中华肥胖与代谢病电子杂志, 2025, 11(01): 1-10.

Ruimin Zhang, Hongmei Zhu, Yanjun Liu. Current status and prospects of clinical research on metabolic and bariatric surgery in China[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2025, 11(01): 1-10.

目的

分析中国肥胖代谢外科领域临床研究现状,包括研究热点和发展趋势,为该学科的未来发展提供科学依据和参考。

方法

基于预先制定的检索策略,对中国知网(CNKI)、Web of Science核心合集(WOSCC)及两大临床试验注册库(ChiCTR和ClinicalTrials.gov)进行减重代谢外科相关文献检索。利用CiteSpace 6.4.R1进行可视化分析,并对注册试验的类型与分布进行描述性统计。

结果

注册试验数量呈现显著增长趋势,尤其是自2019年以来增速明显。通过检索,共纳入521篇中文文章和1 657篇英文文章进行分析。中、英文文章发文量最多的机构分别为暨南大学附属第一医院和上海交通大学,中、英文文章发文量最多的作者分别是张鹏和Lee Wei-Jei。我国中文文章相关研究热点为肥胖、减重手术、糖尿病等;英文文章相关研究热点为morbid obesity、insulin resistance、obstructive sleep apnea等。

结论

中国肥胖代谢外科临床研究在注册试验数量和发表文章数量方面都取得显著进展,但在研究的深度和严谨性方面仍存在提升空间。

Objective

The objective of this study is to analyze the current status of clinical research in the field of metabolic and bariatric surgery in China.This analysis will include research hotspots and development trends.The study will also provide references for the future development of this discipline.

Methods

A predefined search strategy was employed to identify studies related to bariatric and metabolic surgery in the China National Knowledge Infrastructure (CNKI),the Web of Science Core Collection(WOSCC),and two major clinical trial registries (ChiCTR and ClinicalTrials.gov).The visualization analysis was conducted using CiteSpace 6.4.R1,and descriptive statistics were performed on the types and distribution of registered trials.

Results

The number of registered trials exhibited a marked upward trajectory,with a substantial surge since 2019.The analysis included a total of 521 Chinese articles and 1 657 English articles.The institution with the highest publication volume for Chinese articles was the First Affiliated Hospital of Jinan University,while for English articles,it was Shanghai Jiao Tong University.The authors with the most publications were Zhang Peng for Chinese articles and Lee Wei-Jei for English articles.The research hotspots for Chinese articles included obesity,bariatric surgery,and diabetes,while those for English articles were morbid obesity,insulin resistance,and obstructive sleep apnea.

Conclusions

Clinical research in bariatric and metabolic surgery in China has achieved significant progress in terms of the number of registered trials and published articles.However,there remains considerable room for improvement in the depth,innovation,and methodological rigor of research.In the future,it is essential to enhance the design and implementation of high-quality clinical studies to promote the sustained development of this field.

图1 文献筛选流程图
图2 中国肥胖代谢临床研究数量与时间分布情况
表1 ChiCTR 相关临床试验注册排名前十的地区和机构
图3 中国肥胖代谢外科临床研究发文量趋势
图4 中国肥胖代谢外科研究作者合作网络图谱。4A为中国肥胖代谢外科临床研究英文文章作者合作网络图谱;4B为中国肥胖代谢外科临床研究中文文章作者合作网络图谱
图5 中国肥胖代谢外科研究机构合作网络图谱。5A为中国肥胖代谢外科临床研究英文文章研究机构合作网络图谱;5B为中国肥胖代谢外科临床研究中文文章研究机构合作网络图
图6 中国肥胖代谢外科研究关键词共现与聚类图谱。6A为中国肥胖代谢外科临床研究英文文章关键词共现图谱;6B为中国肥胖代谢外科临床研究中文文章关键词共现图;6C为中国肥胖代谢外科临床研究英文文章关键词聚类图谱;6D为中国肥胖代谢外科临床研究中文文章关键词聚类图谱
图7 中国肥胖代谢外科研究关键词聚类时间线图谱。7A为中国肥胖代谢外科研究英文文章关键词聚类时间线;7B为中国肥胖代谢外科研究中文文章关键词聚类时间线
表2 中国肥胖代谢外科临床研究高被引用中文文章分析
时间范围 第一作者 题名 出版年份/年 被引次数/次
朱涵菲 减重代谢术后患者饮食依从性影响因素的质性研究[11] 2021 29
李子建 腹腔镜袖状胃切除术治疗肥胖症及其合并症的疗效分析[12] 2018 28
张茜茜 失效模式与效应分析在预防减重手术患者压力性损伤中的应用及效果[13] 2021 26
朱信强 减重代谢手术及其对全身系统的影响[14] 2018 24
全部时间 李志文 减重代谢术后患者饮食与营养康复方案的构建[15] 2022 24
杨珵璨 减重代谢手术治疗肥胖合并重度阻塞性睡眠呼吸暂停短期疗效分析[16] 2018 23
刘 旭 腹腔镜袖状胃切除患者术后1年的减重效果及其影响因素分析[17] 2021 19
梁 辉 体重指数与减重代谢手术的关系[18] 2016 19
任子淇 减重代谢手术前病人运动行为阶段及其影响因素[19] 2019 18
姜 涛 腹腔镜胃袖状切除联合单吻合口十二指肠回肠旁路术治疗肥胖症及肥胖相关代谢病17例疗效分析[20] 2020 14
朱涵菲 减重代谢术后患者饮食依从性影响因素的质性研究[11] 2021 29
张茜茜 失效模式与效应分析在预防减重手术患者压力性损伤中的应用及效果[13] 2021 26
近5年 李志文 减重代谢术后患者饮食与营养康复方案的构建[15] 2022 24
刘 旭 腹腔镜袖状胃切除患者术后1年的减重效果及其影响因素分析[17] 2021 21
王存川 肥胖与代谢病外科疗效报告的标准规范[21] 2020 17
马艳玲 竖脊肌平面阻滞与椎旁神经阻滞对肥胖患者腹腔镜袖状胃切除术后恢复质量影响的比较[22] 2022 14
王 迪 减重代谢手术对肥胖症患者生活质量影响的Meta分析[23] 2020 14
姜 涛 腹腔镜胃袖状切除联合单吻合口十二指肠回肠旁路术治疗肥胖症及肥胖相关代谢病17例疗效分析[20] 2020 14
林 凤 可视硬性喉镜与可视喉镜在减重手术患者气管插管中的对比研究[24] 2022 12
张晓玲 加速康复外科理念在腹腔镜袖状胃切除术患者中的运用及效果观察[25] 2020 12
表3 中国肥胖代谢外科临床研究高被引用英文文章分析
时间范围 第一作者 题名 出版年份/年 被引次数/次
Liu, RX Gut microbiome and serum metabolomealterations in obesity and after weight-lossintervention[26] 2017 972
Lee, WJ Laparoscopic Roux-en-Y versus minigastricbypass for the treatment of morbidobesity - A prospective randomizedcontrolled clinical trial[27] 2005 362
Lee, WJ Gastric Bypass vs Sleeve Gastrectomy forType 2 Diabetes Mellitus A RandomizedControlled Trial[28] 2011 346
Lee, WJ Laparoscopic Roux-en-Y Vs. Mini-gastricBypass for the Treatment of MorbidObesity: a 10-Year Experience[29] 2012 269
全部时间 Gu, YY Analyses of gut microbiota and plasmabile acids enable stratification of patientsfor antidiabetic treatment[30] 2017 268
Lee, WJ Predicting success of metabolic surgery:age, body mass index, C-peptide, andduration score[31] 2013 190
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Liang,ZW Effect of laparoscopic Roux-en-Ygastric bypass surgery on type 2 diabetesmellitus with hypertension: A randomizedcontrolled trial[33] 2013 156
Lee, WJ Changes in postprandial gut hormonesafter metabolic surgery: a comparison ofgastric bypass and sleeve gastrectomy[34] 2011 147
Zhang,Y A R a n d o m i z e d C l i n i c a l Tr i a l o fLaparoscopic Roux-en-Y Gastric Bypassand Sleeve Gastrectomy for the Treatmentof Morbid Obesity in China: a 5-YearOutcome[35] 2014 135
Zeng, Q Clinical management and treatment ofobesity in China[36] 2021 123
Zhang,X Excess body weight: Novel insights intoits roles in obesity comorbidities[37] 2023 87
近5年 Gu, L A meta-analysis of the medium- andlong-term effects of laparoscopic sleevegastrectomy and laparoscopic Roux-en-Ygastric bypass[38] 2020 67
Song, Y Systemic immune-inflammation index isassociated with hepatic steatosis: Evidencefrom NHANES 2015-2018[39] 2022 64
Ding, L Comparative effectiveness of bariatricsurgeries in patients with obesity andtype 2 diabetes mellitus: A network metaanalysisof randomized controlled trials[40] 2020 53
Soong,T Long-Term Efficacy of Bariatric Surgeryfor the Treatment of Super-Obesity:Comparison of SG, RYGB, and OAGB[41] 2021 52
Huang,J Genomics and phenomics of body massindex reveals a complex disease network[42] 2022 48
Zhang,K Effects of Bariatric Surgery on CancerRisk: Evidence from Meta-analysis[43] 2020 44
Sun, Y Association of Preoperative Body Weightand Weight Loss With Risk of Death AfterBariatric Surgery[44] 2020 42
Nie, X A metagenome-wide association studyof gut microbiome and visceral fataccumulation[45] 2020 42
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