Abstract:

The incidence of both obesity and thyroid cancer is rising worldwide，and obesity has become an important risk factor for thyroid cancer.Studies have shown a significant correlation between obesity and thyroid cancer； however，treatment strategies for patients with both conditions are currently under-researched.This case report describes a 31-year-old female patient admitted to the hospital after a routine check-up detected insulin resistance and a thyroid tumor three days prior.The patient had a body weight of 110 kg and a body mass index （BMI） of 38.5 kg/m².Auxiliary examinations revealed elevated antithyroid peroxidase antibody （TPOAb） levels，and thyroid ultrasound showed bilateral thyroid nodules，with a suspicion of thyroid cancer based on fine-needle aspiration results.A multidisciplinary team at the Department of Bariatric and Metabolic Surgery，Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine successfully performed a single-port laparoscopic sleeve gastrectomy combined with a transoral endoscopic thyroidectomy vestibular approach for thyroid cancer in a single-stage procedure.The surgery lasted 205 minutes，and the patient had an uneventful recovery without significant complications.This combined approach effectively reduced the need for multiple anesthesia and hospital admissions while meeting the patient's needs for cosmetic outcomes and rapid recovery，offering a novel treatment option for patients with obesity and thyroid cancer.

Key words: Obesity, Thyroid cancer, Single-port laparoscopic sleeve gastrectomy, Transoral endoscopic thyroidectomy vestibular approach, Single-stage surgery