Current status and prospects of clinical research on metabolic and bariatric surgery in China

doi:10.3877/cma.j.issn.2095-9605.2025.01.001

Abstract

Abstract:

Objective

The objective of this study is to analyze the current status of clinical research in the field of metabolic and bariatric surgery in China.This analysis will include research hotspots and development trends.The study will also provide references for the future development of this discipline.

Methods

A predefined search strategy was employed to identify studies related to bariatric and metabolic surgery in the China National Knowledge Infrastructure （CNKI），the Web of Science Core Collection（WOSCC），and two major clinical trial registries （ChiCTR and ClinicalTrials.gov）.The visualization analysis was conducted using CiteSpace 6.4.R1，and descriptive statistics were performed on the types and distribution of registered trials.

Results

The number of registered trials exhibited a marked upward trajectory，with a substantial surge since 2019.The analysis included a total of 521 Chinese articles and 1 657 English articles.The institution with the highest publication volume for Chinese articles was the First Affiliated Hospital of Jinan University，while for English articles，it was Shanghai Jiao Tong University.The authors with the most publications were Zhang Peng for Chinese articles and Lee Wei-Jei for English articles.The research hotspots for Chinese articles included obesity，bariatric surgery，and diabetes，while those for English articles were morbid obesity，insulin resistance，and obstructive sleep apnea.

Conclusions

Clinical research in bariatric and metabolic surgery in China has achieved significant progress in terms of the number of registered trials and published articles.However，there remains considerable room for improvement in the depth，innovation，and methodological rigor of research.In the future，it is essential to enhance the design and implementation of high-quality clinical studies to promote the sustained development of this field.

Key words: Metabolic and Bariatric Surgery, Bariatric Surgery, Clinical Research, Obesity, Citespace

Ruimin Zhang, Hongmei Zhu, Yanjun Liu. Current status and prospects of clinical research on metabolic and bariatric surgery in China[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2025, 11(01): 1-10.

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Figures/Tables 10

References 53

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排名	地区	注册数量	排名	机构	注册数量
1	江苏	31	1	暨南大学附属第一医院	17
2	上海	22	2	徐州医科大学附属医院	11
3	广东	21	3	复旦大学附属华山医院	9
4	山东	11	4	南京医科大学第一附属医院	9
5	重庆	10	5	郑州大学附属郑州中心医院	9
6	河南	9	6	重庆医科大学附属第一医院	8
7	浙江	9	7	山东大学齐鲁医院	7
8	北京	7	8	上海市第六人民医院	5
9	四川	6	9	成都市第三人民医院	4
10	湖南	5	10	成都市第五人民医院	4

排名	地区	注册数量	排名	机构	注册数量
1	江苏	31	1	暨南大学附属第一医院	17
2	上海	22	2	徐州医科大学附属医院	11
3	广东	21	3	复旦大学附属华山医院	9
4	山东	11	4	南京医科大学第一附属医院	9
5	重庆	10	5	郑州大学附属郑州中心医院	9
6	河南	9	6	重庆医科大学附属第一医院	8
7	浙江	9	7	山东大学齐鲁医院	7
8	北京	7	8	上海市第六人民医院	5
9	四川	6	9	成都市第三人民医院	4
10	湖南	5	10	成都市第五人民医院	4

时间范围	第一作者	题名	出版年份/年	被引次数/次
	Liu， RX	Gut microbiome and serum metabolomealterations in obesity and after weight-lossintervention^［26］	2017	972
	Lee， WJ	Laparoscopic Roux-en-Y versus minigastricbypass for the treatment of morbidobesity - A prospective randomizedcontrolled clinical trial^［27］	2005	362
	Lee， WJ	Gastric Bypass vs Sleeve Gastrectomy forType 2 Diabetes Mellitus A RandomizedControlled Trial^［28］	2011	346
	Lee， WJ	Laparoscopic Roux-en-Y Vs. Mini-gastricBypass for the Treatment of MorbidObesity： a 10-Year Experience^［29］	2012	269
全部时间	Gu， YY	Analyses of gut microbiota and plasmabile acids enable stratification of patientsfor antidiabetic treatment^［30］	2017	268
	Lee， WJ	Predicting success of metabolic surgery：age， body mass index， C-peptide， andduration score^［31］	2013	190
	Lee， WJ	Effect of laparoscopic mini-gastric bypassfor type 2 diabetes mellitus： Comparisonof BMI＜35 and＞35 kg/m²^［32］	2008	182
	Liang，ZW	Effect of laparoscopic Roux-en-Ygastric bypass surgery on type 2 diabetesmellitus with hypertension： A randomizedcontrolled trial^［33］	2013	156
	Lee， WJ	Changes in postprandial gut hormonesafter metabolic surgery： a comparison ofgastric bypass and sleeve gastrectomy^［34］	2011	147
	Zhang，Y	A R a n d o m i z e d C l i n i c a l Tr i a l o fLaparoscopic Roux-en-Y Gastric Bypassand Sleeve Gastrectomy for the Treatmentof Morbid Obesity in China： a 5-YearOutcome^［35］	2014	135
	Zeng， Q	Clinical management and treatment ofobesity in China^［36］	2021	123
	Zhang，X	Excess body weight： Novel insights intoits roles in obesity comorbidities^［37］	2023	87
近5年	Gu， L	A meta-analysis of the medium- andlong-term effects of laparoscopic sleevegastrectomy and laparoscopic Roux-en-Ygastric bypass^［38］	2020	67
	Song， Y	Systemic immune-inflammation index isassociated with hepatic steatosis： Evidencefrom NHANES 2015-2018^［39］	2022	64
	Ding， L	Comparative effectiveness of bariatricsurgeries in patients with obesity andtype 2 diabetes mellitus： A network metaanalysisof randomized controlled trials^［40］	2020	53
	Soong，T	Long-Term Efficacy of Bariatric Surgeryfor the Treatment of Super-Obesity：Comparison of SG， RYGB， and OAGB^［41］	2021	52
	Huang，J	Genomics and phenomics of body massindex reveals a complex disease network^［42］	2022	48
	Zhang，K	Effects of Bariatric Surgery on CancerRisk： Evidence from Meta-analysis^［43］	2020	44
	Sun， Y	Association of Preoperative Body Weightand Weight Loss With Risk of Death AfterBariatric Surgery^［44］	2020	42
	Nie， X	A metagenome-wide association studyof gut microbiome and visceral fataccumulation^［45］	2020	42

时间范围	第一作者	题名	出版年份/年	被引次数/次
	Liu， RX	Gut microbiome and serum metabolomealterations in obesity and after weight-lossintervention^［26］	2017	972
	Lee， WJ	Laparoscopic Roux-en-Y versus minigastricbypass for the treatment of morbidobesity - A prospective randomizedcontrolled clinical trial^［27］	2005	362
	Lee， WJ	Gastric Bypass vs Sleeve Gastrectomy forType 2 Diabetes Mellitus A RandomizedControlled Trial^［28］	2011	346
	Lee， WJ	Laparoscopic Roux-en-Y Vs. Mini-gastricBypass for the Treatment of MorbidObesity： a 10-Year Experience^［29］	2012	269
全部时间	Gu， YY	Analyses of gut microbiota and plasmabile acids enable stratification of patientsfor antidiabetic treatment^［30］	2017	268
	Lee， WJ	Predicting success of metabolic surgery：age， body mass index， C-peptide， andduration score^［31］	2013	190
	Lee， WJ	Effect of laparoscopic mini-gastric bypassfor type 2 diabetes mellitus： Comparisonof BMI＜35 and＞35 kg/m²^［32］	2008	182
	Liang，ZW	Effect of laparoscopic Roux-en-Ygastric bypass surgery on type 2 diabetesmellitus with hypertension： A randomizedcontrolled trial^［33］	2013	156
	Lee， WJ	Changes in postprandial gut hormonesafter metabolic surgery： a comparison ofgastric bypass and sleeve gastrectomy^［34］	2011	147
	Zhang，Y	A R a n d o m i z e d C l i n i c a l Tr i a l o fLaparoscopic Roux-en-Y Gastric Bypassand Sleeve Gastrectomy for the Treatmentof Morbid Obesity in China： a 5-YearOutcome^［35］	2014	135
	Zeng， Q	Clinical management and treatment ofobesity in China^［36］	2021	123
	Zhang，X	Excess body weight： Novel insights intoits roles in obesity comorbidities^［37］	2023	87
近5年	Gu， L	A meta-analysis of the medium- andlong-term effects of laparoscopic sleevegastrectomy and laparoscopic Roux-en-Ygastric bypass^［38］	2020	67
	Song， Y	Systemic immune-inflammation index isassociated with hepatic steatosis： Evidencefrom NHANES 2015-2018^［39］	2022	64
	Ding， L	Comparative effectiveness of bariatricsurgeries in patients with obesity andtype 2 diabetes mellitus： A network metaanalysisof randomized controlled trials^［40］	2020	53
	Soong，T	Long-Term Efficacy of Bariatric Surgeryfor the Treatment of Super-Obesity：Comparison of SG， RYGB， and OAGB^［41］	2021	52
	Huang，J	Genomics and phenomics of body massindex reveals a complex disease network^［42］	2022	48
	Zhang，K	Effects of Bariatric Surgery on CancerRisk： Evidence from Meta-analysis^［43］	2020	44
	Sun， Y	Association of Preoperative Body Weightand Weight Loss With Risk of Death AfterBariatric Surgery^［44］	2020	42
	Nie， X	A metagenome-wide association studyof gut microbiome and visceral fataccumulation^［45］	2020	42

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