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Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition) ›› 2025, Vol. 11 ›› Issue (01): 70-75. doi: 10.3877/cma.j.issn.2095-9605.2025.01.010

• Reviwes • Previous Articles    

Research progress on the effect of bariatric surgery on intestinal flora and metabolic inflammatory syndrome

Yao Deng1,2, Bicheng Xie1,2, Bian Wu3,4, Danfeng Lan1,2,()   

  1. 1. Department of Gastroenterology,The First People's Hospital of Yunnan Province,650032 Kunming,China
    2. Yunnan Digestive Disease Clinical Medical Center,650032 Kunming,China
    3. Department of Gastrointestinal and Bariatric Metabolic Surgery,The First People's Hospital of Yunnan Province,650032 Kunming,China
    4. Yunnan Key Laboratory of Innovative Application of Traditional Chinese Medicine,650032 Kunming,China
  • Received:2024-05-17 Online:2025-02-28 Published:2025-04-22
  • Contact: Danfeng Lan

Abstract:

Bariatric surgery is currently the most effective way to treat obesity and its related metabolic diseases,and has attracted more and more attention in recent years.Dysbiosis of intestinal flora is an important trigger for metabolic inflammatory process.Bariatric surgery changes the gut microbiota as well as the weight loss,the changes of gut microbiota can improve the blood glucose,blood pressure,blood lipids and insulin resistance of patients to some extent,and help to reduce the inflammatory state and maintain the weight loss of the body.In this review,the effects of bariatric surgery on the intestinal flora,obesity,atherosclerosis (AS),T2DM and NAFLD and the related mechanisms were reviewed.

Key words: Bariatric surgery, Intestinal flora, Atherosclerosis, Type 2 diabetes mellitus, Nonalcoholic fatty liver disease

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