[1] |
Burki T.European Commission classifies obesity as a chronic disease[J].Lancet Diabetes Endocrinol,2021,9(7):418.
|
[2] |
Jin X,Qiu T,Li L,et al.Pathophysiology of obesity and its associated diseases [J].Acta Pharm Sin B,2023,13(6):2403-2424.
|
[3] |
World Obesity Federation.World Obesity Atlas 2024 [EB/OL].(2024-03-04)[2024-03-28].https://data.worldo-besity.org/publications/?cat=22.
|
[4] |
Noria SF,Shelby RD,Atkins KD,et al.Weight Regain After Bariatric Surgery:Scope of the Problem,Causes,Prevention,and Treatment [J].Curr Diab Rep,2023,23(3):31-42.
|
[5] |
Ahmad NN,Robinson S,Kennedy-Martin T,et al.Clinical outcomes associated with anti-obesity medications in real-world practice:A systematic literature review [J].Obes Rev,2021,22(11):e13326.
|
[6] |
Yao H,Zhang A,Li D,et al.Comparative effectiveness of GLP-1 receptor agonists on glycaemic control,body weight,and lipid profile for type 2 diabetes:systematic review and network meta-analysis [J].BMJ,2024,384:e076410.
|
[7] |
Liu Y,Ruan B,Jiang H,et al.The weight-loss effect of GLP-1RAs glucagon-Like peptide-1 receptor agonists in non-diabetic individuals with overweight or obesity:A systematic review with Meta-Analysis and trial sequential analysis of randomized controlled trials [J].Am J Clin Nutr,2023,118(3):614-626.
|
[8] |
Blundell J,Finlayson G,Axelsen M,et al.Effects of once-weekly semaglutide on appetite,energy intake,control of eating,food preference and body weight in subjects with obesity [J].Diabetes Obes Metab,2017,19(9):1242-1251.
|
[9] |
Amaro A,Sugimoto D,Wharton S.Efficacy and safety of semaglutide for weight management:evidence from the STEP program [J].Postgrad Med,2022,134(sup1):5-17.
|
[10] |
Weghuber D,Barrett T,Barrientos-Pérez M,et al.once-weekly semaglutide in adolescents with obesity [J].N Engl J Med,2022,387(24):2245-2257.
|
[11] |
Kosiborod MN,Abildstrøm SZ,Borlaug BA,et al.Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity [J].N Engl J Med,2023,389(12):1069-1084.
|
[12] |
Kosiborod MN,Petrie MC,Borlaug BA,et al.semaglutide in patients with obesity-related heart failure and type 2 diabetes [J].N Engl J Med,2024,390(15):1394-1407.
|
[13] |
Yao H,Zhang A,Li D,et al.Comparative effectiveness of GLP-1 receptor agonists on glycaemic control,body weight,and lipid profile for type 2 diabetes:systematic review and network meta-analysis [J].BMJ,2024,384:e076410.
|
[14] |
Smits MM,Van Raalte DH.Safety of Semaglutide [J].Front Endocrinol (Lausanne),2021,12:645563.
|
[15] |
Nagendra L,Bg H,Sharma M,et al.Semaglutide and cancer:A systematic review and meta-analysis [J].Diabetes Metab Syndr,2023,17(9):102834.
|
[16] |
Baldini G,Phelan KD.The melanocortin pathway and control of appetite-progress and therapeutic implications [J].J Endocrinol,2019,241(1):R1-R33.
|
[17] |
Sharma S,Garfield AS,Shah B,et al.Current mechanistic and pharmacodynamic understanding of melanocortin-4 receptor activation [J].Molecules,2019,24(10):1892.
|
[18] |
Clément K,van den Akker E,Argente J,et al.Efficacy and safety of setmelanotide,an MC4R agonist,in individuals with severe obesity due to LEPR or POMC deficiency:single-arm,open-label,multicentre,phase 3 trials [J].Lancet Diabetes Endocrinol,2020,8(12):960-970.
|
[19] |
Haqq AM,Chung WK,Dollfus H,et al.Efficacy and safety of setmelanotide,a melanocortin-4 receptor agonist,in patients with Bardet-Biedl syndrome and Alström syndrome:a multicentre,randomised,double-blind,placebo-controlled,phase 3 trial with an open-label period [J].Lancet Diabetes Endocrinol,2022,10(12):859-868.
|
[20] |
Trapp CM,Censani M.Setmelanotide:a promising advancement for pediatric patients with rare forms of genetic obesity [J].Curr Opin Endocrinol Diabetes Obes,2023,30(2):136-140.
|
[21] |
Roth CL,Scimia C,Shoemaker AH,et al.Setmelanotide for the treatment of acquired hypothalamic obesity:a phase 2,open-label,multicentre trial [J].Lancet Diabetes Endocrinol,2024,12(6):380-389.
|
[22] |
Pressley H,Cornelio CK,Adams EN.Setmelanotide:A novel targeted treatment for monogenic obesity [J].J Pharm Technol,2022,38(6):368-373.
|
[23] |
Ferraz Barbosa B,Aquino de Moraes FC,Bordignon Barbosa C,et al.Efficacy and safety of setmelanotide,a melanocortin-4 receptor agonist,for obese patients:A systematic review and Meta-analysis [J].J Pers Med,2023,13(10):1460.
|
[24] |
Fisman EZ,Tenenbaum A.The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide:a novel cardiometabolic therapeutic prospect [J].Cardiovasc Diabetol,2021,20(1):225.
|
[25] |
Jastreboff AM,Aronne LJ,Ahmad NN,et al.Tirzepatide once weekly for the treatment of obesity [J].N Engl J Med,2022,387(3):205-216.
|
[26] |
Zhao L,Cheng Z,Lu Y,et al.Tirzepatide for weight reduction in Chinese adults with obesity:The SURMOUNT-CN randomized clinical trial [J].JAMA,2024,332(7):551-560.
|
[27] |
Frías JP,Davies MJ,Rosenstock J,et al.Tirzepatide versus Semaglutide once weekly in patients with type 2 diabetes [J].N Engl J Med,2021,385(6):503-515.
|
[28] |
Sinha R,Papamargaritis D,Sargeant JA,et al.Efficacy and safety of Tirzepatide in Type 2 diabetes and obesity management [J].J Obes Metab Syndr,2023,32(1):25-45.
|
[29] |
Jastreboff AM,Kaplan LM,Frías JP,et al.triple-hormone-receptor agonist retatrutide for obesity — A phase 2 trial [J].N Engl J Med,2023,89(6):514-526.
|
[30] |
Rosenstock J,Frias J,Jastreboff AM,et al.Retatrutide,a GIP,GLP-1 and glucagon receptor agonist,for people with type 2 diabetes:a randomised,double-blind,placebo and active-controlled,parallelgroup,phase 2 trial conducted in the USA [J].Lancet,2023,402(10401):529-544.
|
[31] |
Kaur M,Misra S.A review of an investigational drug retatrutide,a novel triple agonist agent for the treatment of obesity [J].Eur J Clin Pharmacol,2024,80(5):669-676.
|
[32] |
Asiabar AS,Rezaei MA,Jafarzadeh D,et al.The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity:a systematic review [J].Eur J Clin Pharmaco,2024,80(12):1857-1870.
|
[33] |
Li Z,Zhang B,Wang N,et al.A novel peptide protects against dietinduced obesity by suppressing appetite and modulating the gut microbiota [J].Gut,2023,72(4):686-698.
|
[34] |
Chen W,Binbin G,Lidan S,et al.Evolution of peptide YY analogs for the management of type 2 diabetes and obesity [J].Bioorg Chem,2023,140:106808.
|
[35] |
Mathiesen DS,Bagger JI,Knop FK.Long-acting amylin analogues for the management of obesity [J].Curr Opin Endocrinol Diabetes Obes,2022,29(2):183-190.
|
[36] |
Pena-Leon V,Perez-Lois R,Villalon M,et al.Novel mechanisms involved in leptin sensitization in obesity [J].Biochem Pharmacol,2024,223:116129.
|