Influence of sarcopenia on the effect of sleeve gastrectomy in patients with obesity

doi:10.3877/cma.j.issn.2095-9605.2024.04.009

Abstract

Abstract:

Objective

To investigate the effect of sarcopenia on sleeve gastrectomy in patients with obesity.

Methods

A retrospective analysis was performed on the data of 68 patients who received laparoscopic sleeve gastrectomy at the Department of Bariatric and Metabolic Surgery of the First Affiliated Hospital of Xiamen University from 2021 to 2022 and were regularly followed up for 1 year， including 28 males and 40 females.The patients were divided into the sarcopenia group （16 patients） and the nonsarcopenia group （52 patients） according to whether they had sarcopenia.The effect of postoperative weight loss （TWL%） was compared using T-test.

Results

The overall weight loss effect （%TWL） and ameliorative effect of complications in the sarcopenia group was lower than that in the non-sarcopenia group （male：21.73±5.54 vs. 33.50±9.05， P=0.006； female： 25.23±5.71 vs. 36.41±9.69， P＜0.001）.The obesity-related comorbidities of the two groups were improved after surgery， but the improvement rate was not statistically significant （P＞0.05）.

Conclusions

Based on the results of this study， the postoperative effect of bariatric surgery in patients with sarcopenia is worse than that in patients with non-sarcopenia.Preoperative assessment of sarcopenia in patients with obesity has a certain reference value for predicting the effect of weight loss after sleeve gastrectomy.

Key words: Obesity, Sarcopenia, Sarcopenia obesity, Sleeve gastrectomy

Chaojun Wang, Zhiyong Dong, Wan'e Zhao, Songhao Hu, Zhaohui Liu. Influence of sarcopenia on the effect of sleeve gastrectomy in patients with obesity[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2024, 10(04): 283-287.

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Figures/Tables 5

References 17

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组别	年龄		H（cm）		BW（kg）		BMI		FM（kg）		ASM（kg）
组别	M	F	M	F	M	F	M	F	M	F	M	F
肌少症	43.17±6.27	31.80±5.59	172.33±6.09	167.00±4.71	99.67±6.19	106.80±6.61	33.62±2.60	38.42±3.71	45.17±2.04	45.90±2.02	20.17±1.60	14.90±0.99
非肌少症	36.63±8.41	34.50±7.06	169.32±6.68	166.30±4.99	97.27±12.95	101.73±11.86	33.95±4.37	36.89±4.97	44.73±2.43	44.27±2.20	25.50±2.15	22.10±2.19
t	1.763	-1.097	0.997	0.389	0.435	1.279	-0.175	0.889	0.404	2.074	-5.621	-10.005
P
组别	FM%		ASM%		ASMI（kg/m²）		FMI（kg/m²）		ASM/FM%
组别	M	F	M	F	M	F	M	F	M	F
肌少症	45.51±4.11	43.08±2.49	20.27±3.49	14.01±1.44	6.78±0.22	5.34±0.13	15.24±1.06	16.47±0.82	44.66±3.11	32.48±1.93
非肌少症	46.77±6.72	44.11±5.74	26.76±4.75	21.96±2.97	8.94±1.10	8.02±0.96	15.68±1.62	16.06±1.39	57.18±5.73	59.26±6.30
t	-0.436	-0.546	-3.256	-8.102	-4.729	-8.711	-0.628	0.892	-5.103	-13.14
P			0.003	＜0.001	＜0.001	＜0.001	0.535	0.378	＜0.001	＜0.001

组别	年龄		H（cm）		BW（kg）		BMI		FM（kg）		ASM（kg）
组别	M	F	M	F	M	F	M	F	M	F	M	F
肌少症	43.17±6.27	31.80±5.59	172.33±6.09	167.00±4.71	99.67±6.19	106.80±6.61	33.62±2.60	38.42±3.71	45.17±2.04	45.90±2.02	20.17±1.60	14.90±0.99
非肌少症	36.63±8.41	34.50±7.06	169.32±6.68	166.30±4.99	97.27±12.95	101.73±11.86	33.95±4.37	36.89±4.97	44.73±2.43	44.27±2.20	25.50±2.15	22.10±2.19
t	1.763	-1.097	0.997	0.389	0.435	1.279	-0.175	0.889	0.404	2.074	-5.621	-10.005
P
组别	FM%		ASM%		ASMI（kg/m²）		FMI（kg/m²）		ASM/FM%
组别	M	F	M	F	M	F	M	F	M	F
肌少症	45.51±4.11	43.08±2.49	20.27±3.49	14.01±1.44	6.78±0.22	5.34±0.13	15.24±1.06	16.47±0.82	44.66±3.11	32.48±1.93
非肌少症	46.77±6.72	44.11±5.74	26.76±4.75	21.96±2.97	8.94±1.10	8.02±0.96	15.68±1.62	16.06±1.39	57.18±5.73	59.26±6.30
t	-0.436	-0.546	-3.256	-8.102	-4.729	-8.711	-0.628	0.892	-5.103	-13.14
P			0.003	＜0.001	＜0.001	＜0.001	0.535	0.378	＜0.001	＜0.001

组别	FM（kg）		ASM（kg）		FM%		ASM%		ASMI（kg/m²）
组别	M	F	M	F	M	F	M	F	M	F
肌少症	28.83±2.04	28.80±1.87	21.67±2.16	20.40±2.99	29.07±3.30	27.08±2.71	21.74±1.63	19.15±3.00	7.32±0.93	7.34±1.12
非肌少症	28.68±3.37	28.37±3.72	22.32±1.81	23.20±2.22	29.88±4.56	28.37±5.56	23.38±3.88	23.22±4.18	7.83±0.98	8.37±1.11
t	0.104	0.352	-0.752	-3.164	-0.403	-0.698	-0.999	-2.830	-1.132	-2.271
P	0.918	0.727	0.459	0.003	0.690	0.49	0.327	0.007	0.268	0.029
组别	FMI（kg/m²）		ASM/FM%		aWL（kg）		TWL%
组别	M	F	M	F	M	F	M	F
肌少症	9.74±1.03	10.35±0.95	75.81±12.25	71.17±12.18	21.83±6.49	27.20±7.47	21.73±5.54	25.23±5.71
非肌少症	10.02±1.24	10.22±1.56	78.83±11.17	82.94±11.93	33.05±11.35	37.77±13.00	33.50±9.05	36.41±9.69
t	-0.504	0.254	-0.576	-2.688	-2.298	-2.427	-3.011	-3.436
P	0.618	0.801	0.569	0.011	0.030	0.02	0.006	＜0.001

组别	FM（kg）		ASM（kg）		FM%		ASM%		ASMI（kg/m²）
组别	M	F	M	F	M	F	M	F	M	F
肌少症	28.83±2.04	28.80±1.87	21.67±2.16	20.40±2.99	29.07±3.30	27.08±2.71	21.74±1.63	19.15±3.00	7.32±0.93	7.34±1.12
非肌少症	28.68±3.37	28.37±3.72	22.32±1.81	23.20±2.22	29.88±4.56	28.37±5.56	23.38±3.88	23.22±4.18	7.83±0.98	8.37±1.11
t	0.104	0.352	-0.752	-3.164	-0.403	-0.698	-0.999	-2.830	-1.132	-2.271
P	0.918	0.727	0.459	0.003	0.690	0.49	0.327	0.007	0.268	0.029
组别	FMI（kg/m²）		ASM/FM%		aWL（kg）		TWL%
组别	M	F	M	F	M	F	M	F
肌少症	9.74±1.03	10.35±0.95	75.81±12.25	71.17±12.18	21.83±6.49	27.20±7.47	21.73±5.54	25.23±5.71
非肌少症	10.02±1.24	10.22±1.56	78.83±11.17	82.94±11.93	33.05±11.35	37.77±13.00	33.50±9.05	36.41±9.69
t	-0.504	0.254	-0.576	-2.688	-2.298	-2.427	-3.011	-3.436
P	0.618	0.801	0.569	0.011	0.030	0.02	0.006	＜0.001

组别	术前			术后
组别	HBP（%）	T2DM（%）	OSAS（%）	HBP（%）	T2DM（%）	OSAS（%）
肌少症	44	81	94	31	19	31
非肌少症	73	81	92	25	33	42
χ ²	4.70	0.002	0.04	0.25	1.15	0.63
P	0.03	0.97	0.85	0.62	0.28	0.43

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