Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition) ›› 2024, Vol. 10 ›› Issue (04): 276-282. doi: 10.3877/cma.j.issn.2095-9605.2024.04.008

• Young Expert Forum • Previous Articles     Next Articles

Research progress and the relationship between nonalcoholic fatty liver disease and sarcopenic obesity

Yangyang Zhang1, Chuqi Xiang2, Mansheng Zhu3,()   

  1. 1.School of Stomatology, Stomatological Hospital, Southern Medical University, Guangzhou 510515, China
    2.the First College of Clinical Medicine, Southern Medical University, Guangzhou 510515, China
    3.Guangdong Provincial Key Laboratory of Presicion Medicine for Gastrointestinal Tumor, Department of general surgery,Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
  • Received:2024-03-28 Online:2024-11-30 Published:2025-01-06
  • Contact: Mansheng Zhu

Abstract:

Non-alcoholic fatty liver disease (NAFLD) is a pathologic condition manifested by the excessive accumulation of visceral fat in the liver so much so that it gradually progresses to end-stage liver cirrhosis and hepatocellular carcinoma.Some of the NAFLD patients could be comorbid with sarcopenic obesity (SO), especially those of the elderly.As the world's aging population grows, SO has come into the spotlight as a special type of obesity.From the perspective of pathophysiology, SO and NAFLD share many common influencing factors, such as inflammation, aging, insulin resistance, myokines, etc.However, the interactions between these factors remain elusive.Bariatric metabolic surgery has been an effective means to improve glucose and lipid metabolism for young adults and older patients with obesity as well.Clarifying the pathogenesis of sarcopenic obesity and the mechanism of the metabolic disorder process is an important prerequisite for evaluating the feasibility of bariatric and metabolic surgery.In this review, we tried to elucidate the pathogenesis and interrelationship of sarcopenic obesity and NAFLD and provide an overview of the related treatment advancements.

Key words: Non-alcoholic fatty liver disease, Sarcopenic obesity, Aging, Insulin resistance

京ICP 备07035254号-20
Copyright © Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), All Rights Reserved.
Tel: 020-85207287 E-mail: zhfpydxbdzzz@163.com
Powered by Beijing Magtech Co. Ltd