Abstract:
Objective
To evaluate the effectiveness of laparoscopic Roux-en-Y gastric bypass (RYGB)in treating type 2 diabetes mellitus (T2DM) and related complications.
Methods
The clinical data of 70 patients with T2DM who underwent laparoscopic Roux-en-Y gastric bypass from April 2010 to December 2014 was analysed. In the follow up, patients’body mass index (BMI), waist circumference, fasting plasma glucose, Hb1Ac, blood pressure and blood lipid in the postoperative time of 1, 3, 6, 12 and 24 months were checked in time. Preoperative and postoperative indexes were compared by one-factor ANOVA.
Results
The mean age of patients was 46 years (ranging from 25 to 69 years), the mean BMI was 29.3 kg/m2 (ranging from 22.2 to 44.6 kg/m2) and the mean disease course of T2DM was 4.8 years (ranging from 1 month to 16 years). 70 cases were preformed smoothly without deaths. 3 (4.3%) marginal ulcers occurred and were cured with conservative treatment. The postoperative follow up time was from 1 to 24 months, the indexes of BMI, waist circumference, FPG, Hb1Ac were significantly decreased(P＜0.05). In the 70 cases,45 cases(64.3%) showed complete remission of T2DM, 18 cases （25.7%）showed glycemic control, 7 cases (10%)showed improvement, and 0 showed invalidity. The levels of blood pressure and blood lipid were improved significantly for 34 cases with hypertension and 32 cases with hyperlipidemia.
Conclusions
LRYGB has good effects for treating T2DM and relative complications such as hypertension and hyperlipidemia.
Key words:
Laparoscopic Roux-en-Y gastric bypass,
Diabetes mellitus, Type 2,
Hypertension,
Hyperlipidemias
Yu Gao, Jing Chen, Weidong Tong, Chunxue Li, Fan Li, Fang Sun, Xunmei Zhou, Zhencheng Yan, Zhiming Zhu. Application value of laparoscopic Roux-en-Y gastric bypass for type 2 diabetes mellitus and related diseases[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2015, 01(01): 30-33.