To identify the risk factors for moderate-to-severe pain in obesity patients undergoing laparoscopic sleeve gastrectomy surgery (LSG).

The medical records of obesity patients undergoing LSG from March 2020 to December 2021 were retrospectively collected. The patients were 18-65 years old with no gender limitation, ASA Ⅰ-Ⅳ, and all patients were treated with general anesthesia. Preoperative data was collected. Anesthesia time, intraoperative drug, intraoperative fluid volume and other intraoperative data were collected. Numeric Rating Scale (NRS) of postoperative pain and incidence of Postoperative Nausea and Vomiting (PONV) were collected. Patients were divided into moderate-to-severe pain group (NRS≥4 points) and non-moderate-to-severe pain group (NRS<4 points) according to postoperative pain NRS score. Univariate comparison and multivariate logistic regression analysis were used to identify the risk factors of moderate-to-severe pain in obesity patients undergoing LSG according to all perioperative variables.

A total of 323 patients were included in this study, and 30 patients developed moderate-to-severe pain after surgery, with an incidence of 9.29%. The results of multivariate logistic regression analysis showed that Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and PONV were risk factors for moderate-to-severe pain, and the intraoperative use of dezocine was a protective factor for moderate-to-severe pain after surgery (P<0.05).

The history of OSAHS and PONV are risk factors for moderate-to-severe pain in obesity patients undergoing LSG surgery. Intraoperative use of dezocine is a protective factor for moderate-to-severe pain in obesity patients undergoing LSG surgery.