Curative effect analysis of laparoscopic Roux-en-Y gastric bypass to treat type 2 diabetes mellitus

doi:10.3877/cma.j.issn.2095-9605.2015.01.003

Abstract

Abstract:

Objective

To investigate the effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) in treating type 2 diabetes mellitus (T2DM) and the operation essentials of LRYGB.

Methods

The clinical data of 41 T2DM patients who underwent LRYGB in the Fourth Affiliated Hospital of Harbin Medical University during January 2011 to January 2012 was analyzed. Changes of weight, blood glucose and blood lipid levels before and after operations were compared. The measurement data was compared by Independent-Samples t Test.

Results

All procedures were successfully without conversion to open operation. No serious postoperative complications were happened. The operative time was (148±21) min. time to ambulation was (3.0±1.4) d, liquid intake at (3.3±1.2) d, and postoperative hospitalization (15.0±4.1) d. Symptoms of T2DM and metabolic disorders were relieved significantly, and the obesity indexes were also decreased significantly(P＜0.05).

Conclusions

LRYGB is effective for obese T2DM which is worthy of clinical application.

Key words: Diabetes mellitus, Type 2, Laparoscopic Roux-en-Y gastric bypass, Obesity

Chang Liu, Kai Yang, Yanchao Ji, Dong Wang. Curative effect analysis of laparoscopic Roux-en-Y gastric bypass to treat type 2 diabetes mellitus[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2015, 01(01): 7-10.

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References 12

[1]	张敏,聂雷霞,喻娟,等.个性化运动处方在糖尿病腹腔镜胃转流术后患者肠功能恢复中应用的效果[J].解放军护理杂志,2013,30(1):12-15.
[2]	段世刚,刘澎,高放,等.腹腔镜辅助下胃转流术治疗2型糖尿病临床分析[J].武警后勤学院学报:医学版, 2013, 22(1):22-24.
[3]	Perreault L, Pan Q, Mather KJ, et al. Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes Study[J]. Lancet, 2012, 379(9833):2243-2251.
[4]	叶烨,莫建勋,莫春荣,等.经腹腔镜下胃转流术治疗早期肥胖型2型糖尿病的临床观察及护理[J].医学临床研究, 2012, 29(9):1755-1756.
[5]	贺志宽,董文星,孟继明,等.腹腔镜下胃转流术治疗2型糖尿病的疗效分析及可行性研究[J].医学与哲学:临床决策论坛版, 2013,34(491):56-58.
[6]	Schauer PR, Kashyap SR, Wolski K, et a1. Bariatric surgery versus intensive medical therapy in obese patients with diabetes[J]. N Engl J Med, 2012, 366(17):1567-1576.
[7]	Mingrone G, Panunzi S, De Gaetano A, et a1. Bariatric surgery versus conventional medical therapy for type 2 diabetes[J]. N Engl J Med,2012, 366(17):1577-1585.
[8]	高铭,殷浩.减重手术治疗代谢性疾病[J].中华消化外科杂志, 2013,12(12):976-979.
[9]	张晓娟,杜涓,杜潇,等.腹腔镜下胃转流术治疗肥胖型2型糖尿病的疗效分析[J].中国普外基础与临床杂志, 2012, 19(12):1272-1277.
[10]	雒洪志,陈宏,余元龙,等.腹腔镜下 Roux-en-Y 胃空肠转流术治疗肥胖型 2 型糖尿病14 例[J].中华普通外科学文献, 2012, 6 (6):503-506.
[11]	杨景哥,王存川,胡友主,等.腹腔镜Roux-en-Y胃旁路手术治疗超级肥胖症42例[J].中华胃肠外科杂志, 2012, 15(11):1115-1119.
[12]	Aftab H, Risstad H, Søvik TT, et al. Five-year outcome after gastric bypass for morbid obesity in a Norwegian cohort[J]. Surg Obes Relat Dis, 2014, 10(1):71-78.

观察时间	例数	体重（kg）	BMI（kg/m²）	腰围（cm）
术前	21	97±14	34.1±3.9	117±9
术后6个月	21	76±10*	28.7±2.1*	94±6*
术后1年	21	68±8*	27.1±1.8*	92±8*
术后2年	21	68±8*	26.4±2.0*	93±7*
术后3年	21	66±8*	25.6±1.7*	91±7*

观察时间	例数	体重（kg）	BMI（kg/m²）	腰围（cm）
术前	21	97±14	34.1±3.9	117±9
术后6个月	21	76±10*	28.7±2.1*	94±6*
术后1年	21	68±8*	27.1±1.8*	92±8*
术后2年	21	68±8*	26.4±2.0*	93±7*
术后3年	21	66±8*	25.6±1.7*	91±7*

观察时间	例数	FPG（mmol/L)	2hPG（mmol/L)	HbA1c（%）	FCp（μg/L）
术前	21	12.9±2.5	16.1±6.9	9.9±2.2	1.8±0.6
术后2周	21	8.1±2.0*	12.6±3.8*	7.4±1.3*	1.5±0.5
术后3个月	21	6.3±1.7*	11.1±1.8*	7.2±1.4*	1.0±0.5*
术后6个月	21	5.7±1.5*	9.2±1.3*	7.1±1.4*	1.0±0.5*
术后1年	21	5.5±1.3*	7.9±1.6*	6.8±1.3*	0.9±0.4*
术后2年	21	5.7±1.4*	7.7±1.6*	6.7±1.2*	1.0±0.4*
术后3年	21	5.6±1.3*	7.5±1.5*	6.5±1.3*	0.9±0.4*

观察时间	例数	FPG（mmol/L)	2hPG（mmol/L)	HbA1c（%）	FCp（μg/L）
术前	21	12.9±2.5	16.1±6.9	9.9±2.2	1.8±0.6
术后2周	21	8.1±2.0*	12.6±3.8*	7.4±1.3*	1.5±0.5
术后3个月	21	6.3±1.7*	11.1±1.8*	7.2±1.4*	1.0±0.5*
术后6个月	21	5.7±1.5*	9.2±1.3*	7.1±1.4*	1.0±0.5*
术后1年	21	5.5±1.3*	7.9±1.6*	6.8±1.3*	0.9±0.4*
术后2年	21	5.7±1.4*	7.7±1.6*	6.7±1.2*	1.0±0.4*
术后3年	21	5.6±1.3*	7.5±1.5*	6.5±1.3*	0.9±0.4*

观察时间	例数	甘油三酯	总胆固醇	高密度脂蛋白
术前	21	26±13	20±5	3.7±1.1
术后3个月	21	16±12*	18±4*	4.8±1.4*
术后6个月	21	15±11*	17±3*	5.0±1.4*
术后1年	21	14±10*	17±3*	5.2±1.6*
术后2年	21	13±7*	17±3*	5.0±1.4*
术后3年	21	12±6*	17±3*	5.1±1.5*

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