切换至 "中华医学电子期刊资源库"

中华肥胖与代谢病电子杂志 ›› 2023, Vol. 09 ›› Issue (04) : 237 -245. doi: 10.3877/cma.j.issn.2095-9605.2023.04.003

论著

基于CiteSpace的近20年减重对心血管系统影响的可视化分析
彭荣刚1, 杨芳2, 刘倩1, 杨亚娟2, 赵庆2,()   
  1. 1. 214026 无锡,江南大学附属医院心内科
    2. 214023 无锡,南京医科大学附属无锡人民医院CCU
  • 收稿日期:2023-11-22 出版日期:2023-11-30
  • 通信作者: 赵庆
  • 基金资助:
    国家自然科学基金青年项目(82200357); 无锡市科技局项目(Y20212023)

CiteSpace-based visual analysis of the impact of weight loss on the cardiovascular system in the past 20 years

Ronggang Peng1, Fang Yang2, Qian Liu1, Yajuan Yang1, Qing Zhao2,()   

  1. 1. Cardiology Department, Affiliated Hospital of Jiangnan University, Wuxi 214026, China
    2. CCU, Wuxi People’s Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China
  • Received:2023-11-22 Published:2023-11-30
  • Corresponding author: Qing Zhao
引用本文:

彭荣刚, 杨芳, 刘倩, 杨亚娟, 赵庆. 基于CiteSpace的近20年减重对心血管系统影响的可视化分析[J]. 中华肥胖与代谢病电子杂志, 2023, 09(04): 237-245.

Ronggang Peng, Fang Yang, Qian Liu, Yajuan Yang, Qing Zhao. CiteSpace-based visual analysis of the impact of weight loss on the cardiovascular system in the past 20 years[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2023, 09(04): 237-245.

目的

检索2003—2022年减重在心血管领域的相关文献,探究该领域的国际研究热点与发展趋势。

方法

以Web of Science (WOS)为来源检索相关文献,分析年度发文量。运用文献计量学工具CiteSpace对国家、机构、作者、关键词进行可视化分析。

结果

共获得3 946篇文献,来自106个国家、514家研究机构的799位作者在该领域发表研究。发文量呈上升趋势,美国发文量最多,中国发文量位居第六。哈佛大学是发文量最多的研究机构,各研究机构间存在一定的合作。来自美国梅奥医学中心的Lavie CJ教授在该研究领域的产出最多,研究作者以团队为单位合作密切。北京协和医学院是中国发文量最多的研究机构,但与国际相比仍存在较大差距。关键词分析结果显示,减重在心血管领域的研究主要关注运动和减重手术对心衰、冠心病、房颤等心血管疾病的效果及作用机制。

结论

减重在心血管领域的研究受到越来越多关注,且减重对心血管疾病的防治效果在大量研究中得以证实,但是关于"肥胖悖论"的争议仍需进一步探讨减重方式与心血管获益的相关实践与机制。

Objective

To retrieve relevant literature on weight reduction in the cardiovascular field from 2003 to 2022 and explore the international research hotspots and development trends in this field.

Methods

Relevant literature was retrieved from the Web of Science (WOS), and the annual publication volume was analyzed. Visual analysis of countries, institutions, authors, and keywords was conducted using the CiteSpace tool.

Results

3946 articles were obtained from 799 authors affiliated with 514 research institutions in 106 countries. The publication volume showed an increasing trend, with the United States having the highest publication volume and China ranking sixth. Harvard University had the highest publication volume among research institutions, and there was some collaboration between various institutions. Professor Lavie Carl J from the Mayo Clinic in the United States had the highest output in this research field. There was close collaboration among research authors as a team. The Peking Union Medical College had the highest publication volume among Chinese research institutions but still lagged internationally. Keyword analysis indicated that research on weight reduction in the cardiovascular field primarily focused on the effects and mechanisms of exercise and bariatric surgery on cardiovascular diseases such as heart failure, coronary heart disease, and atrial fibrillation.

Conclusions

Research on weight reduction in the cardiovascular field is receiving increasing attention, and the preventive and therapeutic effects of weight reduction on cardiovascular diseases have been confirmed in numerous studies. However, the controversy surrounding the "obesity paradox" requires further exploration of the relevant practices and mechanisms of weight reduction and cardiovascular benefits.

图1 减重对心血管系统影响相关研究的年度发文量注:*表示相应年份发表的重要文献,对该研究领域有重要引领作用[11,12,13,14]
图2 减重对心血管系统影响相关研究的国家共现图谱注:图中节点代表国家,节点越大表示发文量越多;节点间连线表示国家间合作,连线粗细表示合作强弱;颜色代表文献发表年份,左下角颜色从下到上为2003—2022年
表1 减重对心血管系统影响相关研究的发文量排名前十国家
图3 减重对心血管系统影响相关研究的研究机构共现图谱注:图中节点代表机构,节点越大表示发文量越多;节点间连线表示机构间合作,连线粗细表示合作强弱;颜色代表文献发表年份,左下角颜色从下到上为2003—2022年
表2 减重对心血管系统影响相关研究的发文量排名前十研究机构
图4 减重对心血管系统影响相关研究的作者合作共现图谱注:图中节点代表作者,节点越大表示发文量越多;节点间连线表示作者间合作,连线粗细表示合作强弱;颜色代表文献发表年份,左下角颜色从下到上为2003—2022年
图5 减重对心血管系统影响相关研究的关键词共现分析注:图中节点代表关键词,节点越大表示出现频次越高;节点间连线表示关键词共现,连线粗细表示关联强度;颜色代表文献发表年份,左下角颜色从下到上为2003—2022年
图6 减重对心血管系统影响相关研究的关键词聚类分析注:图中每个色块代表一组紧密相关的关键词,聚类标签是聚类内部关键词的代表
表3 减重对心血管系统影响相关研究的关键词聚类标签表
聚类标签 轮廓值 关键词
减重 0.92 减重,舒张功能,T波形态,QRS间期,心衰
心衰 0.95 心衰,心肌重构,共焦显微镜,动脉硬化,心室重塑
房颤 0.94 心房颤动,心包脂肪,肿瘤恶病质,心功能,桥接
运动锻炼 0.95 运动锻炼,心血管疾病,心肺功能,肥胖悖论,内皮功能
先心病 0.86 先心病,心脏手术,重症监护,口服抗凝,定性分析
心血管疾病 0.95 心衰,房颤,心血管疾病,减重术,冠心病
BMI 0.98 身体质量指数,糖尿病,心血管疾病,危险因素,腰围
回顾性研究 0.91 心衰,回顾性研究,酰化肽,信息技术,心外膜脂肪
减重术 0.95 减重术,心衰,心血管疾病,房颤,心肌梗死
冠心病 0.95 心血管疾病,冠心病,减重术,心衰,静脉栓塞
减重 0.96 心衰,减重,质保协议,风险评估,充血性心衰
静脉栓塞 0.96 房颤,静脉栓塞,直接口服抗凝剂,低分子肝素,心脏再同步化治疗
血容量 0.90 心衰,血容量,氯化钠,钠钾氯共转运蛋白,30天再入院
系统评价 0.99 心衰,系统评价,序列分析,GLP-1受体激动剂,动态血压监测
动脉硬化 0.96 动脉硬化,血压,脉搏波传导速度,胰岛素抵抗,儿童肥胖
蛋白质百分比 0.96 减重,蛋白质百分比,右室功能不全,栓塞保护装置,主动脉瓣置换
心肌梗死 1 心肌梗死,心功能,心脏重塑,ACEI,β受体阻滞剂
图7 减重对心血管系统影响相关研究的关键词突现图谱注:Year表示统计起始年,Strength代表关键词突现强度,Begin代表该词最早出现时间,End代表该词最晚出现时间,红色线条代表关键词突现的时间区段
[1]
Chen K, Shen Z, Gu W, et al. Prevalence of obesity and associated complications in China: A cross-sectional, real-world study in 15.8 million adults [J]. Diabetes, obesity & metabolism, 2023, 25(11): 3390-3399.
[2]
中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2022概要[J]. 中国循环杂志, 2023, 38(06): 583-612.
[3]
Larsson SC, Bäck M, Rees JMB, et al. Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study [J]. Eur Heart J, 2020, 41(2): 221-226.
[4]
Fekri N, Khaloo P, Ramezankhani A, et al. Association of body mass index with life expectancy with and without cardiovascular disease [J]. International journal of obesity (2005), 2020, 44(1): 195-203.
[5]
Zhao Y, Yu B Y, Liu Y, et al. Weight reduction and cardiovascular benefits: Protocol for a systematic review and meta-analysis [J]. Medicine, 2018, 97(50): e13246.
[6]
中华医学会心血管病学分会,中国康复医学会心脏预防与康复专业委员会,中国老年学和老年医学会心脏专业委员会等. 中国心血管病一级预防指南 [J]. 中华心血管病杂志, 2020, 48(12): 1000-1038.
[7]
Visseren FLJ, Mach F, Smulders YM, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice [J]. Eur Heart J, 2021, 42(34): 3227-3337.
[8]
Simati S, Kokkinos A, Dalamaga M, et al. Obesity Paradox: Fact or Fiction? [J]. Curr Obes Rep, 2023, 12(2): 75-85.
[9]
Chen C, Chen Y, Hou J, et al. CiteSpace Ⅱ: Detecting and Visualizing Emerging Trends and Transient Patterns in Scientific Literature [J]. Journal of the China Society for Scientific and Technical Information, 2009, 28(3): 401-421.
[10]
姚雪, 徐川平, 李杰, 等. 基于普赖斯定律和二八定律及在线投稿系统构建某科技期刊核心作者用户库 [J]. 编辑学报, 2017, 29(1): 64-66.
[11]
Poirier P, Giles TD, Bray GA, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism [J]. Circulation, 2006, 113(6): 898-918.
[12]
Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society [J]. Circulation, 2014, 129(25 Suppl 2): S102-138.
[13]
Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines [J]. Circulation, 2019, 140(11): e563-e595.
[14]
Powell-Wiley TM, Poirier P, Burke LE, et al. Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association [J]. Circulation, 2021, 143(21): e984-e1010.
[15]
赵宁, 王宇, 王清波, 等. 过去10年我国减重代谢手术的研究进展 [J/CD ]. 中华肥胖与代谢病电子杂志, 2019, 5(3): 123-127.
[16]
Roth GA, Johnson C, Abajobir A, et al. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 [J]. J Am Coll Cardiol, 2017, 70(1): 1-25.
[17]
Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss [J]. J Am Coll Cardiol, 2009, 53(21): 1925-1932.
[18]
Lavie CJ, Ross R, Neeland IJ. Physical activity and fitness vs adiposity and weight loss for the prevention of cardiovascular disease and cancer mortality [J]. Int J Obes (Lond), 2022, 46(12): 2065-2067.
[19]
Doehner W, Gerstein HC, Ried J, et al. Obesity and weight loss are inversely related to mortality and cardiovascular outcome in prediabetes and type 2 diabetes: data from the ORIGIN trial [J]. Eur Heart J, 2020, 41(28): 2668-2677.
[20]
Semlitsch T, Stigler FL, Jeitler K, et al. Management of overweight and obesity in primary care-A systematic overview of international evidence-based guidelines [J]. Obes Rev, 2019, 20(9): 1218-1230.
[21]
Bray G A, Frühbeck G, Ryan D H, et al. Management of obesity [J]. Lancet, 2016, 387(10031): 1947-1956.
[22]
Celik O, Yildiz BO. Obesity and physical exercise [J]. Minerva Endocrinol (Torino), 2021, 46(2): 131-144.
[23]
Oppert JM, Bellicha A, van Baak MA, et al. Exercise training in the management of overweight and obesity in adults: Synthesis of the evidence and recommendations from the European Association for the Study of Obesity Physical Activity Working Group [J]. Obes Rev, 2021, 22 Suppl 4(Suppl 4): e13273.
[24]
Shi Q, Wang Y, Hao Q, et al. Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials [J]. Lancet, 2022, 399(10321): 259-269.
[25]
Neeland IJ, McGuire DK, Sattar N. Cardiovascular Outcomes Trials for Weight Loss Interventions: Another Tool for Cardiovascular Prevention? [J]. Circulation, 2021, 144(17): 1359-1361.
[26]
Jensen SBK, Janus C, Lundgren JR, et al. Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment [J]. Nat Commun, 2022, 13(1): 4770.
[27]
van Rijswijk AS, van Olst N, Schats W, et al. What Is Weight Loss After Bariatric Surgery Expressed in Percentage Total Weight Loss (%TWL)? A Systematic Review [J]. Obes Surg, 2021, 31(8): 3833-3847.
[28]
O'Brien PE, Hindle A, Brennan L, et al. Long-Term Outcomes After Bariatric Surgery: a Systematic Review and Meta-analysis of Weight Loss at 10 or More Years for All Bariatric Procedures and a Single-Centre Review of 20-Year Outcomes After Adjustable Gastric Banding [J]. Obes Surg, 2019, 29(1): 3-14.
[29]
Chi M, Nie Y, Su Y, et al. Effects of weight loss in heart failure patients with overweight and obesity: a systematic review and meta-analysis [J]. Eur J Prev Cardiol, 2023.
[30]
Sundström J, Bruze G, Ottosson J, et al. Weight Loss and Heart Failure: A Nationwide Study of Gastric Bypass Surgery Versus Intensive Lifestyle Treatment[J]. Circulation, 2017, 135(17): 1577-1585.
[31]
Chandrakumar H, Khatun N, Gupta T, et al. The Effects of Bariatric Surgery on Cardiovascular Outcomes and Cardiovascular Mortality: A Systematic Review and Meta-Analysis [J]. Cureus, 2023, 15(2): e34723.
[32]
Fantin F, Giani A, Zoico E, et al. Weight Loss and Hypertension in Obese Subjects [J]. Nutrients, 2019, 11(7): 1667.
[33]
王滢莹, 秦俭, 程丽芳. 肥胖悖论与心血管疾病 [J]. 心血管病学进展, 2022, 43(1): 52-55.
[34]
Tutor AW, Lavie CJ, Kachur S, et al. Updates on obesity and the obesity paradox in cardiovascular diseases [J]. Prog Cardiovasc Dis, 2023, 7(8): 2-10.
[35]
Alebna P L, Mehta A, Yehya A, et al. Update on obesity, the obesity paradox, and obesity management in heart failure [J]. Prog Cardiovasc Dis, 2024, 9: S0033-0620(24)00003-3.
[36]
Bostrom JA, Mottel B, Heffron SP. Medical and Surgical Obesity Treatments and Atherosclerosis: Mechanisms beyond Typical Risk Factors [J]. Curr Atheroscler Rep, 2021, 23(10): 60.
[37]
彭荣刚, 张毅, 宛荣豪, 等. 肥胖症患者减重术后心脏结构功能变化及其机制的研究进展 [J]. 中国心血管杂志, 2020, 25(6): 588-590.
[38]
Lopez-Jimenez F, Almahmeed W, Bays H, et al. Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation [J]. Eur J Prev Cardiol, 2022, 29(17): 2218-37.
[39]
Ahammed MR, Ananya FN. Impact of Weight Loss on Atrial Fibrillation [J]. Cureus, 2023, 15(9): e46232.
[40]
Blüher M, Aras M, Aronne LJ, et al. New insights into the treatment of obesity [J]. Diabetes Obes Metab, 2023, 25(8): 2058-2072.
[41]
Rieth AJ, Hamm CW, Wanner C, et al. [Heart failure protection by SGLT2 inhibitors in patients with type 2 diabetes mellitus: evidence and possible mechanisms: A systematic review [J]. Herz, 2021, 46(Suppl 2): 151-158.
[1] 吴赤球, 韦曙东, 张辉, 严许清, 梅朵卓嘎, 余丹. 驻不同海拔高度高原人员习服后心脏结构和功能变化的超声心动图评估[J]. 中华医学超声杂志(电子版), 2023, 20(06): 588-593.
[2] 赵帅, 王伟, 李瑞奇, 周家杰, 王道荣. 3D腹腔镜下袖状胃切除术治疗肥胖合并2型糖尿病的临床疗效及影响因素分析[J]. 中华普外科手术学杂志(电子版), 2024, 18(02): 146-149.
[3] 纪凯伦, 郝少龙, 孙海涛, 韩威. 减重术后胆囊结石形成机制的新进展[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 100-103.
[4] 牛朝, 李波, 张万福, 靳文帝, 王春晓, 李晓刚. 腹腔镜袖状胃切除联合胆囊切除治疗肥胖合并胆囊结石安全性和疗效[J]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 635-639.
[5] 黄旭, 张圣群, 唐宁, 陈一帆, 黄添隆, 刘唐浩. 反式全肩关节置换术的研究热点分析及新兴趋势预测:一篇基于全文献的文献计量分析[J]. 中华肩肘外科电子杂志, 2023, 11(04): 355-367.
[6] 韦笑韩, 任振, 潘晨, 吴立胜. 减重代谢手术后复胖原因分析及治疗进展[J]. 中华消化病与影像杂志(电子版), 2023, 13(03): 172-178.
[7] 古士锋, 张丽姿, 梁景英, 杜丽丽, 孙雯, 陈敦金. 2011-2021年我国胎盘植入性疾病研究热点:基于CiteSpace可视化分析[J]. 中华产科急救电子杂志, 2023, 12(03): 159-166.
[8] 何青华, 蚁锐娟, 邓碧丽, 杨康娣, 万贻丹, 史桂华, 陈荃敏, 张晶晶. 基于CiteSpace的经颈静脉肝内门体分流术文献计量学分析[J]. 中华介入放射学电子杂志, 2023, 11(04): 330-335.
[9] 高子昂, 段天骄, 谭玉勇, 刘德良, 段天英. 消化内镜隧道技术国内外研究现状及发展趋势的可视化分析[J]. 中华胃肠内镜电子杂志, 2023, 10(03): 159-166.
[10] 董志勇, 王存川. 2022年《ASMBS/IFSO减重与代谢手术适应证指南》解读[J]. 中华肥胖与代谢病电子杂志, 2023, 09(04): 225-230.
[11] 高文星, 刘浩, 赵稳, 李丁昌, 陈鹏, 金露佳, 刘先强, 董光龙. 减重手术后慢性腹痛的原因与对策[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 149-154.
[12] 马俊蓉, 叶艳彬. 减重手术后的营养管理与复胖:现状与思考[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 165-172.
[13] 范晓轩, 王娜, 朱丽花, 王亮. 肥胖相关肿瘤研究进展[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 173-178.
[14] 肖莹莹, 田茵琦, 彭雪梅. 减重手术胃肠道血流量下降的原因及干预措施[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 179-185.
[15] 刘澳, 周菁, 孙永兵, 和俊雅, 林新贝, 乔琦, 李中林, 张建成, 武肖玲, 邹智, 胡扬喜, 肖新广, 吕雪, 李昊, 李永丽. 减重代谢手术后神经影像改变与认知功能评估的研究进展[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 203-208.
阅读次数
全文


摘要