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中华肥胖与代谢病电子杂志 ›› 2023, Vol. 09 ›› Issue (03) : 173 -178. doi: 10.3877/cma.j.issn.2095-9605.2023.03.005

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肥胖相关肿瘤研究进展
范晓轩, 王娜, 朱丽花(), 王亮()   
  1. 510630 广州,暨南大学第一附属医院肿瘤科
    510630 广州,暨南大学第一附属医院风湿免疫科
  • 收稿日期:2023-06-08 出版日期:2023-08-30
  • 通信作者: 朱丽花, 王亮
  • 基金资助:
    广州市基础研究计划市校联合资助项目(SL2023A03J01017)

Research progress of obesity-related tumors

Xiaoxuan Fan, Na Wang, Lihua Zhu(), Liang Wang()   

  1. Department of Oncology, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China
  • Received:2023-06-08 Published:2023-08-30
  • Corresponding author: Lihua Zhu, Liang Wang
引用本文:

范晓轩, 王娜, 朱丽花, 王亮. 肥胖相关肿瘤研究进展[J/OL]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 173-178.

Xiaoxuan Fan, Na Wang, Lihua Zhu, Liang Wang. Research progress of obesity-related tumors[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2023, 09(03): 173-178.

肥胖通过促进慢性系统性炎症、高胰岛素血症、循环类固醇激素升高、血糖和脂质水平升高、促进细胞因子和生长因子的产生等方式促进恶性肿瘤的发生、发展。本文通过对国内外现有文献的回顾,对肥胖相关肿瘤的发生、发展的病理生理机制及减重手术预防肥胖相关肿瘤的现状进行总结。

Obesity can promote the development of tumors through accelerating chronic inflammation, hyperinsulinemia, hypercirculating steroid hormonemia, hypergycemia, hyperlipemia and the production of cytokines and growth factors. Herein, the recent literatures about the development of obesity-related tumors and the phenomenon of obesity paradox are reviewed briefly. And we summarize the current status of bariatric surgery to prevent obesity-related tumors.

图1 肥胖相关肿瘤的发生机制
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