切换至 "中华医学电子期刊资源库"

中华肥胖与代谢病电子杂志 ›› 2016, Vol. 02 ›› Issue (04) : 241 -243. doi: 10.3877/cma.j.issn.2095-9605.2016.04.012

所属专题: 文献

综述

脂联素在肥胖型哮喘发病机制中的研究进展
陆红红1, 翁育清1,(), 曾繁睿1   
  1. 1. 519000 广东,暨南大学附属珠海医院呼吸内科
  • 收稿日期:2016-06-15 出版日期:2016-11-30
  • 通信作者: 翁育清

Research progress of adiponectin in the pathogenesis of obese asthma

Honghong Lu1, Yuqing Weng1(), Fanrui Zeng1   

  • Received:2016-06-15 Published:2016-11-30
  • Corresponding author: Yuqing Weng
引用本文:

陆红红, 翁育清, 曾繁睿. 脂联素在肥胖型哮喘发病机制中的研究进展[J]. 中华肥胖与代谢病电子杂志, 2016, 02(04): 241-243.

Honghong Lu, Yuqing Weng, Fanrui Zeng. Research progress of adiponectin in the pathogenesis of obese asthma[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2016, 02(04): 241-243.

[1]
Boulet LP, FitzGerald JM, Reddel HK. The revised 2014 GINA strategy report: opportunities for change[J]. Curr Opin Pulm Med, 2015, 21(1):1-7.
[2]
Solé D. Obesity and asthma[J]. Rev Paul Pediatr, 2013, 31(2):136-137.
[3]
Miller M, Cho JY, Pham A, et al. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease[J]. J Immunol, 2009, 182(1):684-691.
[4]
Sood A, Shore SA. Adiponectin, leptin, and resistin in asthma: basic mechanisms through population studies[J]. J Allergy (Cairo), 2013(2013):785835.
[5]
Ding Y, Yang H, He H, et al. Plasma adiponectin concentrations and adiponectin gene polymorphisms are associated with bronchial asthma in the Chinese Li population[J]. Iran J Allergy Asthma Immunol, 2015, 14(3):292-297.
[6]
Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity[J]. Biochem Biophys Res Commun, 1999, 257(1):79-83.
[7]
Pajvani UB, Du X, Combs TP, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity[J]. J Biol Chem, 2003, 278(11):9073-9085.
[8]
张艳,魏文青,焦娟, 等. 脂联素的生物学功能研究进展[J]. 中国热带医学, 2013, 13(5):649-654.
[9]
Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects[J]. Nature, 2003, 423(6941):762-769.
[10]
Hug C, Wang J, Ahmad NS, et al. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin[J]. Proc Natl Acad Sci U S A, 2004, 101(28):10308-10313.
[11]
Shore SA, Terry RD, Flynt L, et al. Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice[J]. J Allergy Clin Immunol, 2006, 118(2):389-395.
[12]
Shore SA. Obesity and asthma: possible mechanisms[J]. J Allergy Clin Immunol, 2008, 121(5):1087-1095.
[13]
Yamauchi T, Nio Y, Maki T, et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions[J]. Nat Med, 2007, 13(3):332-339.
[14]
Leiria LO, Martins MA, Saad MJ. Obesity and asthma: beyond T(H)2 inflammation [J]. Metabolism, 2015, 64(2):172-181.
[15]
Juel CT, Ulrik CS. Obesity and asthma: impact on severity, asthma control, and response to therapy[J]. Respir Care, 2013, 58(5):867-873.
[16]
van Huisstede A, Rudolphus A, Castro Cabezas M, et al. Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma[J]. Thorax, 2015, 70(7):659-667.
[17]
Jensen ME, Collins CE, Gibson PG, et al. The obesity phenotype in children with asthma[J]. Paediatr Respir Rev, 2011, 12(3):152-159.
[18]
Oliveira AG, Araujo TG, Carvalho BM, et al. Acute exercise induces a phenotypic switch in adipose tissue macrophage polarization in diet-induced obese rats[J]. Obesity (Silver Spring), 2013, 21(12):2545-2556.
[19]
Claria J, Gonzalez-Periz A, Lopez-Vicario C, et al. New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators[J]. Front Immunol, 2011(2):49.
[20]
Fantuzzi G. Adipose tissue, adipokines, and inflammation[J]. J Allergy Clin Immunol, 2005, 115(5):911-920.
[21]
Wang C. Obesity, inflammation, and lung injury (OILI): the good[J]. Mediators Inflamm, 2014(2014):978463.
[22]
Simons PJ, van den Pangaart PS, Aerts JM, et al. Pro-inflammatory delipidizing cytokines reduce adiponectin secretion from human adipocytes without affecting adiponectin oligomerization[J]. J Endocrinol, 2007, 192(2):289-299.
[23]
Hosogai N, Fukuhara A, Oshima K, et al. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation[J]. Diabetes, 2007, 56(4):901-911.
[24]
Medoff BD, Okamoto Y, Leyton P, et al. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling[J]. Am J Respir Cell Mol Biol, 2009, 41(4):397-406.
[25]
陈秀珍,崇蕾,林罗娜, 等. Adipo/AMPK信号通路的下调参与肥胖型哮喘小鼠的发病[J]. 基础医学与临床, 2016, 36(3):380-385.
[26]
朱述阳,陈建辉,卞宏. 肥胖哮喘大鼠脂联素表达的变化[J]. 中国现代医学杂志, 2009, 19(20):3059-3066.
[27]
de Lima Azambuja R, da Costa Santos Azambuja LS, Costa C, et al. Adiponectin in asthma and obesity: protective agent or risk factor for more severe disease?[J]. Lung, 2015, 193(5):749-755.
[28]
Sood A, Qualls C, Schuyler M, et al. Low serum adiponectin predicts future risk for asthma in women[J]. Am J Respir Crit Care Med, 2012, 186(1):41-47.
[29]
Abdul Wahab A, Maarafiya MM, Soliman A, et al. Serum leptin and adiponectin levels in obese and nonobese asthmatic school children in relation to asthma control[J]. J Allergy (Cairo), 2013(2013):654104.
[30]
Leão da Silva P, de Mello MT, Cheik NC, et al. Reduction in the leptin concentration as a predictor of improvement in lung function in obese adolescents[J]. Obes Facts, 2012, 5(6):806-820.
[31]
da Silva PL, de Mello MT, Cheik NC, et al. Interdisciplinary therapy improves biomarkers profile and lung function in asthmatic obese adolescents[J]. Pediatr Pulmonol, 2012, 47(1):8-17.
[32]
Jartti T, Saarikoski L, Jartti L, et al. Obesity, adipokines and asthma[J]. Allergy, 2009, 64(5):770-777.
[1] 陈腊青, 林佳佳, 毛洪刚, 童冠海, 汪梦娜, 夏红波, 刘卓, 徐海霞, 赵玉华, 张传领. 血清细胞因子及呼出气一氧化氮在哮喘-慢性阻塞性肺疾病重叠综合征中的临床意义[J]. 中华危重症医学杂志(电子版), 2023, 16(04): 316-320.
[2] 杨皓媛, 龚杰, 邹青伟, 阮航. 哮喘孕妇的母婴不良妊娠结局研究现状[J]. 中华妇幼临床医学杂志(电子版), 2023, 19(05): 522-529.
[3] 娄丽丽, 刘瀚旻. 儿童哮喘易感基因及表观遗传学研究现状[J]. 中华妇幼临床医学杂志(电子版), 2023, 19(03): 249-255.
[4] 冯丹艳, 曹晓辉, 史玉霞. 血清脂联素与胎盘亮氨酸氨肽酶对妊娠期糖尿病患者妊娠结局的影响[J]. 中华妇幼临床医学杂志(电子版), 2023, 19(03): 302-308.
[5] 聂锋, 李婉珍. 不打针不吃药不输液徒手治疗糖尿病一例报道[J]. 中华普外科手术学杂志(电子版), 2023, 17(03): 354-354.
[6] 张荷连, 刘禹, 李丹妮, 彭茹, 杨彩蝶, 窦恒, 吴红梅. 心理障碍对重度哮喘患者的疾病控制及生活工作质量的影响[J]. 中华肺部疾病杂志(电子版), 2023, 16(04): 589-591.
[7] 刘佳铭, 孙晓容, 文健, 何晓丽, 任茂玲. 有氧运动对成人哮喘肺功能、生活质量以及哮喘控制影响的Meta分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(04): 592-595.
[8] 谭玲芳, 周克兵. 基于生物信息学整合鉴定与支气管哮喘相关的潜在诊断生物标志物[J]. 中华肺部疾病杂志(电子版), 2023, 16(03): 329-334.
[9] 路东明, 陈建华, 艾月琴. 布地格福吸入气雾剂治疗支气管哮喘的临床分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(03): 361-363.
[10] 刘汶睿, 高丽娜, 于书娴, 周建刚. 支气管哮喘患者血清IL-27与IFN-γ及肺功能相关性分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(02): 224-226.
[11] 苏慧媛, 宋洪涛, 高巍, 武忠. 针刺治疗单纯性肥胖的系统评价和Meta分析[J]. 中华针灸电子杂志, 2023, 12(03): 123-128.
[12] 董正妮, 张珑耀. 穴位埋线疗法治疗单纯性肥胖的研究进展[J]. 中华针灸电子杂志, 2023, 12(02): 57-61.
[13] 刘澳, 周菁, 孙永兵, 和俊雅, 林新贝, 乔琦, 李中林, 张建成, 武肖玲, 邹智, 胡扬喜, 肖新广, 吕雪, 李昊, 李永丽. 减重代谢手术后神经影像改变与认知功能评估的研究进展[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 203-208.
[14] 陈笑梅, 陈文辉, 赵宛鄂, 郭婕, 苏超, 付志菊, 杨华, 董志勇, 王存川. 可吞咽自吸收新型胃内球囊治疗轻度肥胖症:一例病例报告[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 215-217.
[15] 闫海, 邵怡凯, 姚琪远. 减重代谢外科在心血管疾病防治中的临床意义与前景[J]. 中华肥胖与代谢病电子杂志, 2023, 09(02): 137-142.
阅读次数
全文


摘要