To investigate the efficacy of laparoscopic sleeve gastrectomy (LSG) for the treatment of obese type 2 diabetes mellitus (T2DM).

Clinical data of 34 patients with obese type 2 diabetes mellitus undergoing metabolic surgery in China-Japan Friendship Hospital affiliated to Jilin Univerity between December 2015 and October 2016 were retrospectively studied. The informed consents of all patients were obtained and the local ethical committee approval had been received. The patient's body weight indexes (body weight, BMI, %EWL), blood glucose indexes[fasting plasma glucose (FPG), glycosylated hemoglobin (HbAlc), 2-hour postprandial blood glucose (2hPG)] were measured at 1, 3, 6 months after operation and compared with preoperative levels.

All the patients completed operation under laparoscopy. The average operative time was (69.0±9.2) min, and the average blood loss (18.0±2.7) ml. The patient was able to ambulate lst day after surgery, and water was available on the 3rd day after the operation. The whole diet was started on the 4th day after the operation, and the normal diet was gradually restored, and the average length of hospital stay was (8.0±3.0) day. At preoperative and postoperative 1, 3 and 6 months the weight of patients respectively were (96.9±15.5) kg, 86.8±13.7) kg, (80.6±12.5) kg, (75.5±11.2) kg, the BMI of patients respectively were (33.9±4.3) kg/m², (30.4±3.9) kg/m², (29.9±11.5) kg/m², (26.5±3.5) kg/m², at postoperative 1, 3 and 6 months %EWL of patients respectively were (33.2±12.7) %, (54.0±21.3) %, (70.1±26.7) %, The body weight and BMI at 1,3,6 months after surgery were significantly lower (all P<0.05). At the same time, %EWL showed significant increasing trend (P<0.05). 1 month after surgery, HbAlc was reduced to (6.4±0.6) % from the preoperative period (8.2±1.9) % (P<0.05), and the FPG was reduced to (7.4±4.0) mmol/L from preoperative (9.1±2.7) mmol/L (P<0.05).Clinical complete remission rate of T2DM was 88.2% (30/34), and clinical partial remission rate was 11.8% (4/34)at the 6-month follow-up.

For obese type 2 diabetes, LSG can significantly reduce the patient's weight and improve diabetes effedively in the short term.