Correlation of metabolic syndrome and stress urinary incontinence in women

doi:10.3877/cma.j.issn.2095-9605.2023.02.006

Abstract

Abstract:

Objective

To compare the frequency of Metabolic syndrome (MS) in patients with and without stress urinary incontinence (SUI), and analyzed the relationship between MS and SUI.

Methods

The components of MS were evaluated in 126 women and in 150 women without SUI at Peking University Shougang Hospital from September 2018 to September 2021.BMI, fasting blood glucose (FBG), Glycated hemoglobin (HbA1c), triglyceride (TG), cholesterol (TC), high-density lipoprotein (HDL-C), Low-density lipoprotein (LDL-C) and blood pressure (BP) were compared between the two groups. According to the degree of Sui, the patients were divided into three groups: mild SUI group, moderate SUI group and severe SUI group. The incidence of MS were compared among the three groups. The correlation between Sui and MS was analyzed.

Results

The MS diagnosis was more prevalent in patients with SUI, with the frequency being 55.6% in the SUI group and 41.3% in the control group. Each MS component was evaluated, and the body mass index, FBG and TG were significantly higher in the SUI group compared with the control group (P<0.05). The women in the SUI group showed an average HDL cholesterol value statistically lower than the women in the control group (P<0.05), and no significant differences found in systolic blood pressure (SBP) and diastolic blood pressure (DBP). The incidence of MS in severe SUI group was the highest, and the incidence of MS in moderate SUI group was higher than that in mild SUI group. Logistic regression analysis showed that MS was a risk factor for increasing SUI.

Conclusions

MS frequency was higher in patients with SUI,and MS is a risk factor to increase the degree of SUI.

Key words: Metabolic syndrome, Stress urinary incontinence, Obesity, Diabetes

Lianchao Jin, Bing Yang, Zhe Zhou, Dongliang Pan, Zunke Xie. Correlation of metabolic syndrome and stress urinary incontinence in women[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2023, 09(02): 109-113.

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References 20

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指标	SUI组	对照组	t/χ²值	P值
年龄（岁）	56.52±9.19	55.83±10.27	0.577	0.564
怀孕（次）	2.12±1.23	1.81±0.99	2.285	0.023
分娩（次）	1.87±1.08	1.63±0.85	2.050	0.041
顺产（次）	1.62±1.28	1.29±1.17	2.212	0.028
MS（%）	70（55.6）	62（41.3）	5.551	0.022
BMI（ kg/m²）	25.69±2.00	24.86±2.23	3.231	0.001
TC（mmol/L）	4.73±1.02	4.59±0.97	1.157	0.248
HDL-C（mmol/L）	0.98±0.39	1.10±0.40	2.409	0.017
LDL-C（mmol/L）	2.27±0.51	2.19±0.53	1.319	0.188
TG（mmol/L）	1.79±0.51	1.63±0.49	2.858	0.005
FPG（mmol/L）	6.18±1.05	5.91±1.01	2.121	0.035
HbA1c（%）	5.90±1.15	5.61±0.88	2.328	0.021
SBP（mmHg）	132.84±18.90	130.85±18.17	0.889	0.375
DBP（mmHg）	76.84±12.86	73.89±14.48	1.773	0.077

指标	SUI组	对照组	t/χ²值	P值
年龄（岁）	56.52±9.19	55.83±10.27	0.577	0.564
怀孕（次）	2.12±1.23	1.81±0.99	2.285	0.023
分娩（次）	1.87±1.08	1.63±0.85	2.050	0.041
顺产（次）	1.62±1.28	1.29±1.17	2.212	0.028
MS（%）	70（55.6）	62（41.3）	5.551	0.022
BMI（ kg/m²）	25.69±2.00	24.86±2.23	3.231	0.001
TC（mmol/L）	4.73±1.02	4.59±0.97	1.157	0.248
HDL-C（mmol/L）	0.98±0.39	1.10±0.40	2.409	0.017
LDL-C（mmol/L）	2.27±0.51	2.19±0.53	1.319	0.188
TG（mmol/L）	1.79±0.51	1.63±0.49	2.858	0.005
FPG（mmol/L）	6.18±1.05	5.91±1.01	2.121	0.035
HbA1c（%）	5.90±1.15	5.61±0.88	2.328	0.021
SBP（mmHg）	132.84±18.90	130.85±18.17	0.889	0.375
DBP（mmHg）	76.84±12.86	73.89±14.48	1.773	0.077

例数	轻度组（n=55）	中度组（n=51）	重度组（n=20）	χ²值	P值
肥胖	27（49.09）	27（52.94）	16（80.00）	5.912	0.052
糖尿病	20（36.36）	23（45.10）	11（55.00）	2.256	0.324
高脂血症	29（52.73）	28（54.90）	12（60.00）	0.314	0.855
高血压	16（29.09）	17（33.33）	9（45.00）	1.670	0.434
MS	25（45.45）	32（62.75）	15（75.00）	6.326	0.042

例数	轻度组（n=55）	中度组（n=51）	重度组（n=20）	χ²值	P值
肥胖	27（49.09）	27（52.94）	16（80.00）	5.912	0.052
糖尿病	20（36.36）	23（45.10）	11（55.00）	2.256	0.324
高脂血症	29（52.73）	28（54.90）	12（60.00）	0.314	0.855
高血压	16（29.09）	17（33.33）	9（45.00）	1.670	0.434
MS	25（45.45）	32（62.75）	15（75.00）	6.326	0.042

项目	β值	S.E	Wald	OR	95% CI	P值
SUI程度= 0	1.554	0.669	5.393	4.733	1.274-17.573	0.020
SUI程度= 1	0.995	0.440	5.107	2.705	0.132-1.857	0.024
MS	1.665	0.675	6.085	5.287	1.408-19.857	0.014
BMI	1.498	0.776	3.731	4.473	0.978-20.457	0.053
糖尿病	-0.894	0.694	1.662	0.409	0.105-1.592	0.197
高脂血症	0.016	0.358	0.002	1.016	0.685-0.718	0.963
高血压	-0.085	0.219	0. 151	0.918	0.598-1.410	0.698

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