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Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition) ›› 2022, Vol. 08 ›› Issue (01): 46-51. doi: 10.3877/cma.j.issn.2095-9605.2022.01.008

• Review • Previous Articles     Next Articles

The effects of short chain fatty acids on host metabolism

XiaoZhuo Tan1, Chong Cao1, YiKai Shao1, QiYuan Yao1,()   

  1. 1. Department of General Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China
  • Received:2022-01-09 Online:2022-02-28 Published:2022-04-28
  • Contact: QiYuan Yao

Abstract:

Growing evidence has revealeda strong association of the gut microbiotawithmetabolic diseases of human beings. Literature has recently proposed an important role for the key metabolites deriving from the gut microbiota, namely short chain fatty acids (SCFAs), to maintain host's metabolic homeostasis. SCFAs regulate systemic metabolism by affecting physiology of different tissues and organs. Moreover, it can be use as therapies for some metabolic diseases with broad prospects. In this Review, we discuss the current findings on how SCFAs contribute to the metabolic health of host.

Key words: Gut microbiota, Short-chain fatty acids (SCFAs), Metabolic diseases, Obesity

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