Effect of intervention based on personalized continuous nursing model on anxiety, depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease

doi:10.3877/cma.j.issn.2095-9605.2021.03.006

Abstract

Abstract:

Objective

To explore the effect of personalized continuous nursing intervention on anxiety, depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease.

Methods

A total of 60 patients with type 2 diabetes and coronary heart disease in Maoming People's Hospital from May 2019 to October 2020 were selected as the research objects. They were randomly divided into a treatment group and a control group, with 30 cases in each group. The control group received routine care, while the treatment group received Adopt personalized continuous care model. The SAS and SDS scores, serum h-CRP, IL-6, IL-10, NO, VEGF and ET-1 levels of the two groups were compared before intervention and after 6 months of intervention.

Results

After 6 months of intervention, the SAS and SDS scores of the treatment group were significantly lower than those of the control group (P<0.05), and the h-CRP and IL-6 of the treatment group were significantly lower than those of the control group, while IL-10 was significantly higher. Compared with the control group (P<0.05); after 6 months in the treatment group, the NO and VEGF of the patients were significantly higher than the control group, while ET-1 was significantly lower than the control group, the difference was statistically significant (P<0.05).

Conclusions

Personalized continuation of nursing is a nursing method that effectively promotes the relief of anxiety and depression in patients with type 2 diabetes and coronary heart disease and improves the endothelial function of patients.

Key words: Type 2 diabetes, Personalized, Continuous care, Coronary heart disease, Anxiety and depression, Endothelial function

Min Huang, Haiyan Liang, Wenjing Lao. Effect of intervention based on personalized continuous nursing model on anxiety, depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2021, 07(03): 170-174.

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References 11

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组别	例数（n）	性别（男/女）	BMI（kg/m²）	平均年龄（岁）	平均病程（年）
处理组	30	17/13	21.4±1.7	55.6±4.5	3.9±1.1
对照组	30	14/16	21.5±1.4	56.1±4.7	4.0±1.2
t/χ²值		0.601	0.249	0.421	0.336
P值		0.438	0.804	0.675	0.738

组别	例数（n）	性别（男/女）	BMI（kg/m²）	平均年龄（岁）	平均病程（年）
处理组	30	17/13	21.4±1.7	55.6±4.5	3.9±1.1
对照组	30	14/16	21.5±1.4	56.1±4.7	4.0±1.2
t/χ²值		0.601	0.249	0.421	0.336
P值		0.438	0.804	0.675	0.738

组别	例数（n）	SAS		SDS
组别	例数（n）	干预前	3月后	干预前	3月后
处理组	30	61.8±4.8	35.5±4.6^*#	63.4±5.6	41.7±4.9^*#
对照组	30	62.2±5.3	49.1±4.4^#	62.1±5.3	55.4±5.6^#
t值		0.306	11.702	0.923	10.084
P值		0.760	<0.001	0.360	<0.001

组别	例数（n）	SAS		SDS
组别	例数（n）	干预前	3月后	干预前	3月后
处理组	30	61.8±4.8	35.5±4.6^*#	63.4±5.6	41.7±4.9^*#
对照组	30	62.2±5.3	49.1±4.4^#	62.1±5.3	55.4±5.6^#
t值		0.306	11.702	0.923	10.084
P值		0.760	<0.001	0.360	<0.001

组别		h-CRP（ng/L）	IL-6（ng/L）	IL-10（ng/L）
处理组（n=30）	干预前	13.6±3.2	14.7±2.9	236.7±34.2
处理组（n=30）	3月后	6.7±1.6^*#	7.7±1.5^*#	427.8±54.7^*#
对照组（n=30）	干预前	13.8±2.9	14.5±2.7	240.2±31.7
对照组（n=30）	3月后	11.3±1.5^#	10.5±2.1^#	282.3±39.2^#

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