Clinical effects and preliminary experience of high intensity focused ultrasound in the treatment of uterine myoma with abdominal obesity

doi:10.3877/cma.j.issn.2095-9605.2019.03.003

Abstract

Abstract:

Objective

To explore the clinical effects and preliminary experience of high intensity focused ultrasound in the treatment of uterine myoma with abdominal obesity.

Methods

Five patients with uterine myoma and abdominal obesity who received HIFU treatment from May 20, 2019 to May 2019 in Guangdong Women and Children Hospital were selected. Analyze the treatment time, focusing time, power and recored the adverse reaction of five patients after teratment. The changes in uterine size, fibroid size and ablation area were compared pretreatment, 24 hours posttreatment and 6 months posttreatment.

Results

The average ablation rate of 5 patients was 59.8% at 24 hours posttreatment. The volume of uterus and fibroid volume decreased by 19.2% and 37.6% at 6 months posttreatment. Five patients had mild abdominal pain and lumbosacral pain after treatment. Three patients had vaginal secretion after treatment, and one patient had subcutaneous induration after treatment.

Conclusions

It had great clinical effects and safety of HIFU in the treatment of uterine fibroids with abdominal obesity, and worthy of further application.

Key words: High Intensity Focused Ultrasound, Uterine myoma, Abdominal obesity, Clinical effects, Safety

Shanshan Liu, Xu Zhang, Xiaochang Tan, Min Shen, Lianqing Huang, Xiping Luo. Clinical effects and preliminary experience of high intensity focused ultrasound in the treatment of uterine myoma with abdominal obesity[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2019, 05(03): 137-141.

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References 20

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项目	患者1	患者2	患者3	患者4	患者5	平均值
年龄（岁）	46	28	46	39	44	40.6±7.6
身高（cm）	156	147	162	152	157	154.8±5.6
体重（kg）	65	71	70	53	63	64.4±7.2
BMI（kg/m²）	26.7	32.9	26.7	23	25.6	26.9±3.6
腹围（cm）	98	101	103	80	80	92.4±11.5
治疗时间（h）	1.8	1.5	2.5	3.6	2.3	2.3±0.8
聚焦时间（s）	625	527	618	1056	855	736.2±215.9
功率（W）	280	280	300	300	280	288±11.0

项目	患者1	患者2	患者3	患者4	患者5	平均值
年龄（岁）	46	28	46	39	44	40.6±7.6
身高（cm）	156	147	162	152	157	154.8±5.6
体重（kg）	65	71	70	53	63	64.4±7.2
BMI（kg/m²）	26.7	32.9	26.7	23	25.6	26.9±3.6
腹围（cm）	98	101	103	80	80	92.4±11.5
治疗时间（h）	1.8	1.5	2.5	3.6	2.3	2.3±0.8
聚焦时间（s）	625	527	618	1056	855	736.2±215.9
功率（W）	280	280	300	300	280	288±11.0

指标	治疗前	治疗后24 h	治疗后6月
子宫体积（cm³）	162.9±42.0	197.6±45.5	134.8±51.3
肌瘤体积（cm³）	46.7±39.8	50.9±42.2	25.8±21.4
无灌注区体积（cm³）	/	28.8±28.5	13.2±21.2

指标	治疗前	治疗后24 h	治疗后6月
子宫体积（cm³）	162.9±42.0	197.6±45.5	134.8±51.3
肌瘤体积（cm³）	46.7±39.8	50.9±42.2	25.8±21.4
无灌注区体积（cm³）	/	28.8±28.5	13.2±21.2

并发症	例数
皮肤烫伤	0
皮下硬结	1
阴道分泌物	3
腰骶部酸胀	5
腹痛	5
血尿	0
排尿困难	0
正常组织及脏器损伤	0

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