[1] |
Kivimäki M, Strandberg T, Pentti J, et al. Body-mass index and risk of obesity-related complex multimorbidity: an observational multicohort study [J]. The Lancet Diabetes & Endocrinology, 2022, 10(4): 253-263.
|
[2] |
Chen K, Shen Z, Gu W, et al. Prevalence of obesity and associated complications in China: A cross‐sectional, real‐world study in 15.8 million adults [J]. Diabetes, Obesity and Metabolism, 2023, 25(11): 3390-3399.
|
[3] |
Machluf Y, Farkash R, Fink D, et al. Asthma severity and heterogeneity: Insights from prevalence trends and associated demographic variables and anthropometric indices among Israeli adolescents [J]. Journal of Asthma, 2018, 55(8): 826-836.
|
[4] |
Gomez-Llorente M, Romero R, Chueca N, et al. Obesity and Asthma: A Missing Link[J]. International Journal of Molecular Sciences, 2017, 18(7): 1490.
|
[5] |
刘斌, 梁彦超, 刘双柏, 等. 肥胖和支气管哮喘之间的因果关联:一项双向孟德尔随机化研究 [J]. 国际呼吸杂志, 2023, 43(12):1421-1427.
|
[6] |
Li J, Zhu L, Wei Y, et al. Association between adiposity measures and COPD risk in Chinese adults [J]. European Respiratory Journal, 2020,55(4): 1901899.
|
[7] |
Huang T, Lin BM, Markt SC, et al. Sex differences in the associations of obstructive sleep apnoea with epidemiological factors [J]. European Respiratory Journal, 2018, 51(3): 1702421.
|
[8] |
Balachandran JS, Masa JF, Mokhlesi B. Obesity Hypoventilation Syndrome [J]. Sleep Medicine Clinics, 2014, 9(3): 341-347.
|
[9] |
Hedenstierna G, Santesson J. Breathing mechanics, dead space and gas exchange in the extremely obese, breathing spontaneously and during anaesthesia with intermittent positive pressure ventilation [J]. Acta Anaesthesiologica Scandinavica, 1976, 20(3): 248-254.
|
[10] |
Pelosi P, Croci M, Ravagnan I, et al. Total Respiratory System, Lung, and Chest Wall Mechanics in Sedated-Paralyzed Postoperative Morbidly Obese Patients [J]. Chest, 1996, 109(1): 144-151.
|
[11] |
Pelosi P, Croci M, Ravagnan I, et al. The effects of body mass on lung volumes, respiratory mechanics, and gas exchange during general anesthesia [J]. Anesthesia & Analgesia, 1998, 87(3): 654-660.
|
[12] |
Farkas GA, Schlenker EH. Pulmonary ventilation and mechanics in morbidly obese Zucker rats. [J]. American Journal of Respiratory and Critical Care Medicine, 1994, 150(2): 356-362.
|
[13] |
Inselman LS, Chander A, Spitzer AR. Diminished Lung Compliance and Elevated Surfactant Lipids and Proteins in Nutritionally Obese Young Rats [J]. Lung, 2004,182(2): 101-117.
|
[14] |
Shanmugasundaram K, Bade G, Sampath M, et al. Effect of obesity on airway mechanics [J]. Indian Journal of Endocrinology and Metabolism, 2023, 27(2): 161.
|
[15] |
Peters U, Subramanian M, Chapman DG, et al. BMI but not central obesity predisposes to airway closure during bronchoconstriction [J]. Respirology, 2019, 24(6): 543-550.
|
[16] |
Dixon AE, Poynter ME, Garrow OJ, et al. Peripheral Airway Dysfunction in Obesity and Obese Asthma [J]. Chest, 2023, 163(4): 753-762.
|
[17] |
Elliot JG, Donovan GM, Wang KCW, et al. Fatty airways: implications for obstructive disease [J]. European Respiratory Journal, 2019, 54(6): 1900857.
|
[18] |
Bhatawadekar SA, Peters U, Walsh RR, et al. Central airway collapse is related to obesity independent of asthma phenotype [J]. Respirology, 2021, 26(4): 334-341.
|
[19] |
De Soomer K, Vaerenberg H, Weyler J, et al. Effects of Weight Change and Weight Cycling on Lung Function in Overweight and Obese Adults [J]. Annals of the American Thoracic Society, 2024, 21(1): 47-55.
|
[20] |
Hegewald MJ. Impact of obesity on pulmonary function: current understanding and knowledge gaps [J]. Current Opinion in Pulmonary Medicine, 2021, 27(2): 132-140.
|
[21] |
Jones RL, Nzekwu MU. The Effects of Body Mass Index on Lung Volumes [J]. Chest, 2006, 130(3): 827-833.
|
[22] |
Zeng X, Liu D, An Z, et al. Obesity parameters in relation to lung function levels in a large Chinese rural adult population [J]. Epidemiology and Health, 2021, 43: e2021047.
|
[23] |
Forno E, Han Y, Mullen J, et al. Overweight, obesity, and lung function in children and adults—a meta-analysis [J]. The Journal of Allergy and Clinical Immunology: In Practice, 2018, 6(2): 570-581.
|
[24] |
Marillier M, Bernard A, Reimao G, et al. Breathing at Extremes [J]. Chest, 2020, 158(4): 1576-1585.
|
[25] |
McNeill JN, Lau ES, Zern EK, et al. Association of obesity-related inflammatory pathways with lung function and exercise capacity [J]. Respiratory Medicine, 2021, 183: 106434.
|
[26] |
Park Y, Kim J, Kim YS, et al. Longitudinal association between adiposity changes and lung function deterioration [J]. Respiratory Research, 2023, 24(1).
|
[27] |
Alqarni AA, Aldhahir AM, Alqahtani JS, et al. Spirometry profiles of overweight and obese individuals with unexplained dyspnea in Saudi Arabia [J]. Heliyon, 2024, 10(3): e24935.
|
[28] |
Hou P, Pi Y, Jiao Z, et al. Association of Body Composition with Pulmonary Function in Ningxia: The China Northwest Cohort [J]. Diabetes Metab Syndr Obes, 2022, 15: 3243-3254.
|
[29] |
Zhang R, Zhou J, Cai Y, et al. Non-linear association of anthropometric measurements and pulmonary function [J]. Scientific Reports, 2021, 11(1): 14596.
|
[30] |
Wang Y, Li Z, Li F. Nonlinear relationship between visceral adiposity index and lung function: a population-based study [J]. Respiratory Research, 2021, 22(1):161.
|
[31] |
Liu J, Xu H, Cupples LA, et al. The impact of obesity on lung function measurements and respiratory disease: A Mendelian randomization study [J]. Annals of Human Genetics, 2023, 87(4): 174-183.
|
[32] |
Skaaby T, Taylor AE, Thuesen BH, et al. Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization [J]. Allergy, 2018, 73(1): 153-164.
|
[33] |
Wielscher M, Amaral AFS, van der Plaat D, et al. Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment [J]. Genome Medicine, 2021, 13(1): 104.
|
[34] |
Backman H, Blomberg A, Lundquist A, et al. Lung Function Trajectories and Associated Mortality among Adults with and without Airway Obstruction [J]. American Journal of Respiratory and Critical Care Medicine, 2023, 208(10): 1063-1074.
|
[35] |
Zhang X, Gray AR, Hancox RJ. Distinct trajectories of lung function from childhood to mid-adulthood [J]. Thorax, 2024, 2023-220436.
|
[36] |
Carsin A, Garcia-Aymerich J, Accordini S, et al. Spirometric patterns in young and middle-aged adults: a 20-year European study [J]. Thorax, 2024, 79(2): 153-162.
|
[37] |
Dharmage SC, Bui DS, Walters EH, et al. Lifetime spirometry patterns of obstruction and restriction, and their risk factors and outcomes: a prospective cohort study [J]. The Lancet Respiratory Medicine, 2023, 11(3): 273-282.
|
[38] |
Lee J, Park HK, Kwon M, et al. The effect of metabolic health and obesity on lung function: A cross sectional study of 114,143 participants from Kangbuk Samsung Health Study [J]. PLOS ONE, 2022, 17(4): e266885.
|
[39] |
朱蕾, 陈荣昌. 成人肺功能诊断规范中国专家共识 [J]. 临床肺科杂志, 2022, 27(7): 973-981.
|
[40] |
Holley AB, Carbone T, Holtzclaw AW, et al. Obesity-related Changes in Diffusing Capacity and Transfer Coefficient of the Lung for Carbon Monoxide and Resulting Patterns of Abnormality across Reference Equations [J]. Annals of the American Thoracic Society, 2023, 20(7): 969-975.
|
[41] |
Enache I, Oswald-Mammosser M, Scarfone S, et al. Impact of Altered Alveolar Volume on the Diffusing Capacity of the Lung for Carbon Monoxide in Obesity [J]. Respiration, 2011, 81(3): 217-222.
|
[42] |
Holley HS, Milic-Emili J, Becklake MR, et al. Regional Distribution of Pulmonary Ventilation and Perfusion in Obesity [J]. Journal of Clinical Investigation, 1967, 46(4): 475-481.
|
[43] |
Rivas E, Arismendi E, Agustí A, et al. Ventilation/Perfusion Distribution Abnormalities In Morbidly Obese Subjects Before and After Bariatric Surgery [J]. Chest, 2015, 147(4): 1127-1134.
|
[44] |
Shore SA. Obesity, airway hyperresponsiveness, and inflammation [J]. Journal of Applied Physiology, 2010, 108(3): 735-743.
|
[45] |
Celedón JC, Palmer LJ, Litonjua AA, et al. Body Mass Index and Asthma in Adults in Families of Subjects with Asthma in Anqing, China [J]. American Journal of Respiratory and Critical Care Medicine, 2001, 164(10): 1835-1840.
|
[46] |
Chinn S. Relation of bronchial responsiveness to body mass index in the ECRHS [J]. Thorax, 2002, 57(12): 1028-1033.
|
[47] |
Kim M, Cho S, Jung J, et al. Association between obesity and lung function changes by sex and age in adults with asthma [J]. Journal of Asthma, 2022, 59(1): 59-69.
|
[48] |
Behazin N, Jones SB, Cohen RI, et al. Respiratory restriction and elevated pleural and esophageal pressures in morbid obesity [J]. Journal of Applied Physiology, 2010, 108(1): 212-218.
|
[49] |
Steier J, Lunt A, Hart N, et al. Observational study of the effect of obesity on lung volumes [J]. Thorax, 2014, 69(8): 752-759.
|
[50] |
Lo Mauro A, Tringali G, Codecasa F, et al. Pulmonary and chest wall function in obese adults [J]. Scientific Reports, 2023, 13(1): 17753.
|
[51] |
Molani Gol R, Rafraf M. Association between abdominal obesity and pulmonary function in apparently healthy adults: A systematic review [J]. Obesity Research & Clinical Practice, 2021, 15(5): 415-424.
|
[52] |
Svartengren M, Cai G, Malinovschi A, et al. The impact of body mass index, central obesity and physical activity on lung function: results of the EpiHealth study [J]. ERJ Open Research, 2020, 6(4): 214-2020.
|
[53] |
Buras ED, Converso-Baran K, Davis CS, et al. Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction [J]. Diabetes, 2019, 68(1): 45-56.
|
[54] |
Yu X, Huang Y, Feng Y, et al. Association of Muscle Fat Content and Muscle Mass With Impaired Lung Function in Young Adults With Obesity: Evaluation With MRI [J]. Academic Radiology, 2024, 31(1): 9-18.
|
[55] |
Park HK, Lee SH, Lee SY, et al. Relationships between lung function decline and skeletal muscle and fat mass changes: a longitudinal study in healthy individuals [J]. Journal of Cachexia, Sarcopenia and Muscle, 2021, 12(6): 2145-2153.
|
[56] |
龚凤英, 胡雯婧. 脂肪组织:一个具有高度异质性和可塑性的内分泌和免疫器官 [J]. 中华糖尿病杂志, 2022, 14(12): 1469-1474.
|
[57] |
Peters MC, Schiebler ML, Cardet JC, et al. The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma [J]. American Journal of Respiratory and Critical Care Medicine, 2022, 206(9): 1096-1106.
|
[58] |
Scott HA, Ng SH, McLoughlin RF, et al. Effect of obesity on airway and systemic inflammation in adults with asthma: a systematic review and meta-analysis [J]. Thorax, 2023, 78(10): 957-965.
|
[59] |
Baltieri L, Cazzo E, Oliveira Modena DA, et al. Correlation between levels of adipokines and inflammatory mediators with spirometric parameters in individuals with obesity and symptoms of asthma: Cross-sectional study [J]. Pulmonology, 2022, 28(2): 105-112.
|
[60] |
Palma G, Sorice GP, Genchi VA, et al. Adipose Tissue Inflammation and Pulmonary Dysfunction in Obesity [J]. International Journal of Molecular Sciences, 2022, 23(13): 7349.
|
[61] |
Umetsu DT. Mechanisms by which obesity impacts upon asthma [J]. Thorax, 2017, 72(2): 174-177.
|
[62] |
Park YH, Oh EY, Han H, et al. Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway [J]. Experimental & Molecular Medicine, 2019, 51(5): 1-12.
|
[63] |
Han H, Chung SI, Park HJ, et al. Obesity-induced Vitamin D Deficiency Contributes to Lung Fibrosis and Airway Hyperresponsiveness [J]. American Journal of Respiratory Cell and Molecular Biology, 2021, 64(3): 357-367.
|
[64] |
Mair KM, Harvey KY, Henry AD, et al. Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension [J]. European Respiratory Journal, 2019, 53(6): 1801524
|
[65] |
Pu S, Yin L, Wen B, et al. The Association of Body Mass Index With the Risk of Pulmonary Hypertension in Adults: A Systematic Review and Meta-Analysis of Observational Studies [J]. Frontiers in Medicine, 2022, 8: 680223.
|
[66] |
Frank RC, Min J, Abdelghany M, et al. Obesity Is Associated With Pulmonary Hypertension and Modifies Outcomes [J]. Journal of the American Heart Association, 2020, 9(5): e014195.
|
[67] |
Reddy YNV, Anantha-Narayanan M, Obokata M, et al. Hemodynamic Effects of Weight Loss in Obesity [J]. JACC: Heart Failure, 2019, 7(8): 678-687.
|
[68] |
Naeije R, Richter MJ, Rubin LJ. The physiological basis of pulmonary arterial hypertension [J]. European Respiratory Journal, 2022, 59(6): 2102334.
|
[69] |
Thayer TE, Levinson RT, Huang S, et al. BMI Is Causally Associated With Pulmonary Artery Pressure But Not Hemodynamic Evidence of Pulmonary Vascular Remodeling [J]. Chest, 2021, 159(1): 302-310.
|
[70] |
Low AT, Medford ARL, Millar AB, et al. Lung function in pulmonary hypertension [J]. Respiratory Medicine, 2015, 109(10): 1244-1249.
|
[71] |
Shrine N, Guyatt AL, Erzurumluoglu AM, et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries [J]. Nature Genetics, 2019, 51(3): 481-493.
|
[72] |
Zhao X, Qiao D, Yang C, et al. Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants [J]. Nature Communications, 2020, 11(1): 5182.
|
[73] |
Zhu Z, Li J, Si J, et al. A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity [J]. European Respiratory Journal, 2021, 58(4): 2100199.
|
[74] |
Peralta GP, Marcon A, Carsin A, et al. Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study [J]. Thorax, 2020, 75(4): 313-320.
|
[75] |
Copley SJ, Jones LC, Soneji ND, et al. Lung parenchymal and tracheal ct morphology: evaluation before and after bariatric surgery [J]. Radiology, 2020, 294(3): 669-675.
|