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中华肥胖与代谢病电子杂志 ›› 2023, Vol. 09 ›› Issue (03) : 209 -214. doi: 10.3877/cma.j.issn.2095-9605.2023.03.011

综述

醛固酮与脂肪关系的研究进展
秦梧耀, 高文惠, 崔浩, 尚吉文()   
  1. 030032 太原,山西医科大学第三医院(山西白求恩医院/山西医学科学院/同济山西医院)
  • 收稿日期:2023-05-06 出版日期:2023-08-30
  • 通信作者: 尚吉文
  • 基金资助:
    山西省重点研发项目(202203021211072)

Research progress of correlation between aldosterone and adipocytes

Wuyao Qin, Wenhui Gao, Hao Cui, Jiwen Shang()   

  1. Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical SciencesTongji Shanxi Hospital, Taiyuan 030032, China
  • Received:2023-05-06 Published:2023-08-30
  • Corresponding author: Jiwen Shang
引用本文:

秦梧耀, 高文惠, 崔浩, 尚吉文. 醛固酮与脂肪关系的研究进展[J]. 中华肥胖与代谢病电子杂志, 2023, 09(03): 209-214.

Wuyao Qin, Wenhui Gao, Hao Cui, Jiwen Shang. Research progress of correlation between aldosterone and adipocytes[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2023, 09(03): 209-214.

醛固酮主要是由肾上腺皮质球状带产生的一种盐皮质激素,目前研究发现醛固酮与脂肪细胞之间有紧密联系。而醛固酮增多,尤其是原发性醛固酮增多症对患者脂代谢的影响以及与肥胖的关系仍在研究中。本文就醛固酮与脂肪细胞间的联系,以及原发性醛固酮增多症与肥胖等代谢性疾病相关性的研究进展作一综述。

Aldosterone is a salt corticosteroid produced primarily by the globus pallidus of the adrenal cortex. Current studies have found a strong association between aldosterone and adipocytes. The effect of increased aldosterone, especially in patients with primary aldosteronism, on lipid metabolism and the relationship with obesity is still under investigation. This article reviews the research progress on the association between aldosterone and adipocytes and the correlation between patients with primary aldosteronism and obesity and other metabolic diseases.

图1 肾上腺素合成醛固酮的主要调节因子以及脂肪细胞衍生因子的关系
图2 脂肪、醛固酮、MR激活的关系
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