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中华肥胖与代谢病电子杂志 ›› 2024, Vol. 10 ›› Issue (02) : 120 -126. doi: 10.3877/cma.j.issn.2095-9605.2024.02.008

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肥胖与结直肠癌的研究进展
庄建彬1,(), 杨明建1   
  1. 1. 300170,天津,天津市第三中心医院胃肠肛肠外科
  • 收稿日期:2024-03-10 出版日期:2024-05-30
  • 通信作者: 庄建彬

Research progress of obesity and colorectal cancer

Jianbin Zhuang1,(), Mingjian Yang1   

  1. 1. Department of Gastroentero-anorectal surgery, The Third Central Hospital of Tianjin, Tianjin 300170, China
  • Received:2024-03-10 Published:2024-05-30
  • Corresponding author: Jianbin Zhuang
引用本文:

庄建彬, 杨明建. 肥胖与结直肠癌的研究进展[J]. 中华肥胖与代谢病电子杂志, 2024, 10(02): 120-126.

Jianbin Zhuang, Mingjian Yang. Research progress of obesity and colorectal cancer[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2024, 10(02): 120-126.

肥胖不仅会引起糖尿病、高血脂等代谢性疾病,也会促进肿瘤的发生。肥胖与结直肠癌之间存在着多种共同的危险因素,越来越多的研究表明肥胖参与结直肠癌的发生发展,但作用机制尚未完全明确。此外减重代谢手术和药物的发展影响着肥胖相关性肿瘤的治疗手段。本文对肥胖和结直肠癌的关系、作用机制、治疗现状及预防措施进行综述。

Obesity can not only cause metabolic diseases such as diabetes and hyperlipidemia, but also promote the occurrence of tumors. There are many common risk factors between obesity and colorectal cancer. More and more studies have shown that obesity is involved in the occurrence and development of colorectal cancer, but the mechanism of action has not been fully clarified. In addition, the development of metabolic and bariatric surgery and drugs is affecting the treatment of obesity-related tumors. This article reviews the relationship, mechanism, treatment and prevention of obesity and colorectal cancer.

图1 肥胖促进CRC发生的相关作用机制
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