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中华肥胖与代谢病电子杂志 ›› 2023, Vol. 09 ›› Issue (04) : 267 -273. doi: 10.3877/cma.j.issn.2095-9605.2023.04.007

综述

代谢综合征与动脉粥样硬化性疾病相关性研究现状与进展
钱昊1, 李振振1,()   
  1. 1. 570311 海口,海南医学院附属海南医院·海南省人民医院血管外科
  • 收稿日期:2023-11-01 出版日期:2023-11-30
  • 通信作者: 李振振
  • 基金资助:
    海南省自然科学基金资助项目(820MS135); 海南省卫生健康委员会2023年度省级临床重点学科(临床医学中心)建设单位基金资助项目(琼卫医函[2022]341号); 海南省卫生健康科技创新联合项目(WSJK2024MS209)

Current status and research progress of the association between metabolic syndrome and atherosclerotic disease

Hao Qian1, Zhenzhen Li1,()   

  1. 1. Department of Vascular Surgery, Affiliated Hainan Hospital of Hainan Medical University, Hainan Provincial People's Hospital, Haikou 570311, China
  • Received:2023-11-01 Published:2023-11-30
  • Corresponding author: Zhenzhen Li
引用本文:

钱昊, 李振振. 代谢综合征与动脉粥样硬化性疾病相关性研究现状与进展[J/OL]. 中华肥胖与代谢病电子杂志, 2023, 09(04): 267-273.

Hao Qian, Zhenzhen Li. Current status and research progress of the association between metabolic syndrome and atherosclerotic disease[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2023, 09(04): 267-273.

代谢综合征(MetS)是一组代谢异常的集合,并与心血管疾病(ASCVD)、2型糖尿病(T2DM)等健康问题紧密相关。随着对MetS认知的不断深入,其诊断标准日益精确化。MetS与动脉粥样硬化性疾病的相关性背后涉及氧化应激(OS)、胰岛素抵抗(IR)、长期慢性炎症和血脂紊乱等诸多机制。本文将深入探讨MetS与动脉粥样硬化及其各方面的联系。此外,未来研究需明确MetS导致动脉粥样硬化的具体机制,评估潜在的生物标志物,并持续优化治疗策略。

Metabolic syndrome (MetS) is a collection of metabolic abnormalities that are strongly associated with health issues such as arteriosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus (T2DM). With the growing awareness of MetS and the increasing precision of its diagnostic criteria, the widespread prevalence of MetS is indisputable. The mechanisms behind the association of MetS with atherosclerotic diseases involve oxidative stress (OS), insulin resistance (IR), long-term chronic inflammation, and dyslipidemia, among many others. This paper will delve into the link between MetS and atherosclerosis and its various aspects. In addition, future studies need to clarify the specific mechanisms by which MetS leads to atherosclerosis, evaluate potential biomarkers, and continue to optimize therapeutic strategies.

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