| [1] |
WHO. Obesity and overweight [EB/OL]. (2021-06-30) [2022/08/16].
URL
|
| [2] |
中国疾病预防控制中心营养数据年鉴. 超重肥胖 [EB/OL]. [2022/08/16].
URL
|
| [3] |
Aspray TJ, Hill TR. Osteoporosis and the Ageing Skeleton [J]. Subcell Biochem, 2019, 91: 453-476.
|
| [4] |
国家卫生健康委员会. 首次中国居民骨质疏松症流行病学调查结果 [EB/OL]. (2018-10-19) [2022/8/16].
URL
|
| [5] |
Yu F, Xia W. The epidemiology of osteoporosis, associated fragility fractures, and management gap in China [J]. Arch Osteoporos, 2019, 14(1): 32.
|
| [6] |
Gkastaris K, Goulis DG, Potoupnis M, et al. Obesity, osteoporosis and bone metabolism [J]. J Musculoskelet Neuronal Interact, 2020, 20(3): 372-381.
|
| [7] |
Premaor MO, Comim FV, Compston JE. Obesity and fractures [J]. Arquivos Brasileiros de Endocrinologia & Metabologia, 2014, 5(58): 470-477.
|
| [8] |
Curtis EM, Moon RJ, Harvey NC, et al. The impact of fragility fracture and approaches to osteoporosis risk assessment worldwide [J]. Bone, 2017, 104: 29-38.
|
| [9] |
Fassio A, Idolazzi L, Rossini M, et al. The obesity paradox and osteoporosis [J]. Eat Weight Disord, 2018, 23(3): 293-302.
|
| [10] |
Rinonapoli G, Pace V, Ruggiero C, et al. Obesity and bone: a complex relationship [J]. Int J Mol Sci, 2021, 22(24): 13662.
|
| [11] |
Proietto J. Obesity and Bone [J]. F1000Res, 2020, 9: 1111.
|
| [12] |
[Walsh JS, Vilaca T. Obesity, type 2 diabetes and bone in adults [J]. Calcif Tissue Int, 2017, 100(5): 528-535.
|
| [13] |
Evans AL, Paggiosi MA, Eastell R, et al. Bone density, microstructure and strength in obese and normal weight men and women in younger and older adulthood [J]. J Bone Miner Res, 2015, 30(5): 920-928.
|
| [14] |
Jose A, Cherian KE, Nandyal MB, et al. Trabecular bone score and bone mineral density in postmenopausal women with morbid obesity-a clinical paradox [J]. Med Sci (Basel), 2021, 9(4): 69.
|
| [15] |
Li Y. Association between obesity and bone mineral density in middle-aged adults [J]. J Orthop Surg Res, 2022, 17(1): 268.
|
| [16] |
Hajihosseinali M, Arjmand N, Shirazi-Adl A. Effect of body weight on spinal loads in various activities: a personalized biomechanical modeling approach [J]. J Biomech, 2015, 48(2): 276-282.
|
| [17] |
Ghezelbash F, Shirazi-Adl A, Plamondon A, et al. Obesity and obesity shape markedly influence spine biomechanics: a subject-specific risk assessment model [J]. Ann Biomed Eng, 2017, 45(10): 2373-2382.
|
| [18] |
Turcotte AF, O'Connor S, Morin SN, et al. Association between obesity and risk of fracture, bone mineral density and bone quality in adults: a systematic review and meta-analysis [J]. PLoS One, 2021, 16(6): e252487.
|
| [19] |
Yi SW, Bae JH, Kim YM, et al. Relationship between body mass index and fracture risk at different skeletal sites: a nationwide cohort study [J]. Arch Osteoporos, 2022, 17(1): 99.
|
| [20] |
Hjelle AM, Apalset EM, Gjertsen JE, et al. Associations of overweight, obesity and osteoporosis with ankle fractures [J]. BMC Musculoskelet Disord, 2021, 22(1): 723.
|
| [21] |
Li X, Gong X, Jiang W. Abdominal obesity and risk of hip fracture: a meta-analysis of prospective studies [J]. Osteoporos Int, 2017, 28(10): 2747-2757.
|
| [22] |
Benedick A, Audet MA, Vallier HA. The effect of obesity on post-operative complications and functional outcomes after surgical treatment of torsional ankle fracture: A matched cohort study [J]. Injury, 2020, 51(8): 1893-1898.
|
| [23] |
Chaudhry YP, Rao SS, Puvanesarajah V, et al. Complications and 30-day mortality rate after hip fracture surgery in superobese patients [J]. J Orthop Trauma, 2021, 35(6): 322-328.
|
| [24] |
Chaves PDHN, de Lima CI, Chaves DHLC, et al. Fracture risk after bariatric surgery: a systematic literature review and meta-analysis [J]. Endocr Pract, 2022, 28(1): 58-69.
|
| [25] |
Mele C, Caputo M, Ferrero A, et al. Bone response to weight loss following bariatric surgery [J]. Front Endocrinol (Lausanne), 2022, 13: 921353.
|
| [26] |
Paccou J, Caiazzo R, Lespessailles E, et al. Bariatric surgery and osteoporosis [J]. Calcif Tissue Int, 2022, 110(5): 576-591.
|
| [27] |
Zouhal H, Berro AJ, Kazwini S, et al. Effects of exercise training on bone health parameters in individuals with obesity: a systematic review and meta-analysis [J]. Front Physiol, 2021, 12: 807110.
|
| [28] |
Molina J, Morgan EL. Obesity and Orthopedic Issues [J]. 2022.
|
| [29] |
Himes C L, Reynolds S L. Effect of obesity on falls, injury, and disability [J]. J Am Geriatr Soc, 2012, 60(1): 124-129.
|
| [30] |
Neri GR, Oliveira Silvia S, Dario Juliana B, et al. Does obesity increase the risk and severity of falls in people aged 60 years and older? A systematic review and meta-analysis of observational studies [J]. J Gerontol A Biol Sci Med Sci, 2020, 75(5): 952-960.
|
| [31] |
Mitchell R J, Lord S R, Harvey L A, et al. Obesity and falls in older people: mediating effects of disease, sedentary behavior, mood, pain and medication use [J]. Arch Gerontol Geriatr, 2015, 60(1): 52-58.
|
| [32] |
Garcia PA, Queiroz LL, Caetano M, et al. Obesity is associated with postural balance on unstable surfaces but not with fear of falling in older adults [J]. Braz J Phys Ther, 2021, 25(3): 311-318.
|
| [33] |
Blain H, Miot S, Bernard PL. How can we prevent falls? [J]. 2021: 273-290.
|
| [34] |
Ilich JZ, Kelly OJ, Inglis JE, et al. Interrelationship among muscle, fat, and bone: connecting the dots on cellular, hormonal, and whole body levels [J]. Ageing Res Rev, 2014, 15: 51-60.
|
| [35] |
Szlejf C, Parra-Rodriguez L, Rosas-Carrasco O. Osteosarcopenic obesity: Prevalence and relation with frailty and physical performance in middle-aged and older women [J]. J Am Med Dir Assoc, 2017, 18(8): 731-733.
|
| [36] |
Ilich JZ, Inglis JE, Kelly OJ, et al. Osteosarcopenic obesity is associated with reduced handgrip strength, walking abilities, and balance in postmenopausal women [J]. Osteoporos Int, 2015, 26(11): 2587-2595.
|
| [37] |
Scott D, Seibel M, Cumming R, et al. Does combined osteopenia/osteoporosis and sarcopenia confer greater risk of falls and fracture than either condition alone in older men? the concord health and ageing in men project [J]. J Gerontol A Biol Sci Med Sci, 2019, 74(6): 827-834.
|
| [38] |
Nie YZ, Yan ZQ, Yin H, et al. Osteosarcopenic obesity and its components-osteoporosis, sarcopenia, and obesity-are associated with blood cell count-derived inflammation indices in older Chinese people [J]. BMC Geriatr, 2022, 22(1): 532.
|
| [39] |
Kelly OJ, Gilman JC, Boschiero D, et al. Osteosarcopenic obesity: current knowledge, revised identification criteria and treatment principles [J]. Nutrients, 2019, 11(4).
|
| [40] |
Cheung YM, Joham A, Marks S, et al. The obesity paradox: an endocrine perspective [J]. Intern Med J, 2017, 47(7): 727-733.
|
| [41] |
Obradovic M, Sudar-Milovanovic E, Soskic S, et al. Leptin and Obesity: Role and Clinical Implication [J]. Front Endocrinol (Lausanne), 2021, 12: 585887.
|
| [42] |
Chen XX, Yang T. Roles of leptin in bone metabolism and bone diseases [J]. J Bone Miner Metab, 2015, 33(5): 474-485.
|
| [43] |
Bao D, Ma Y, Zhang X, et al. Preliminary characterization of a leptin receptor knockout rat created by CRISPR/Cas9 System [J]. Sci Rep, 2015, 5: 15942.
|
| [44] |
Lee NJ, Qi Y, Enriquez RF, et al. Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay [J]. Int J Obes (Lond), 2020, 44(10): 2149-2164.
|
| [45] |
Kirk B, Feehan J, Lombardi G, et al. Muscle, bone, and fat crosstalk: the biological role of myokines, osteokines, and adipokines [J]. Curr Osteoporos Rep, 2020, 18(4): 388-400.
|
| [46] |
Choi HM, Doss HM, Kim KS. Multifaceted physiological roles of adiponectin in inflammation and diseases [J]. Int J Mol Sci, 2020, 21(4).
|
| [47] |
Yang J, Park OJ, Kim J, et al. Adiponectin deficiency triggers bone loss by up-regulation of osteoclastogenesis and down-regulation of osteoblastogenesis [J]. Front Endocrinol (Lausanne), 2019, 10: 815.
|
| [48] |
Leeners B, Geary N, Tobler PN, et al. Ovarian hormones and obesity [J]. Hum Reprod Update, 2017, 23(3): 300-321.
|
| [49] |
Walsh JS, Evans AL, Bowles S, et al. Free 25-hydroxyvitamin D is low in obesity, but there are no adverse associations with bone health [J]. Am J Clin Nutr, 2016, 103(6): 1465-1471.
|
| [50] |
Samuel L, Borrell LN. The effect of body mass index on optimal vitamin D status in U.S. adults: the National Health and Nutrition Examination Survey 2001-2006 [J]. Ann Epidemiol, 2013, 23(7): 409-414.
|
| [51] |
Kawai T, Autieri MV, Scalia R. Adipose tissue inflammation and metabolic dysfunction in obesity [J]. Am J Physiol Cell Physiol, 2021, 320(3): C375-C391.
|
| [52] |
Oliveira MC, Vullings J, van de Loo F. Osteoporosis and osteoarthritis are two sides of the same coin paid for obesity [J]. Nutrition, 2020, 70: 110486.
|
| [53] |
Kitaura H, Marahleh A, Ohori F, et al. Osteocyte-related cytokines regulate osteoclast formation and bone resorption [J]. Int J Mol Sci, 2020, 21(14).
|
| [54] |
Roy B, Curtis ME, Fears LS, et al. Molecular mechanisms of obesity-induced osteoporosis and muscle atrophy [J]. Front Physiol, 2016, 7: 439.
|
| [55] |
Lin H, Sohn J, Shen H, et al. Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing [J]. Biomaterials, 2019, 203: 96-110.
|
| [56] |
Tencerova M, Frost M, Figeac F, et al. Obesity-associated hypermetabolism and accelerated senescence of bone marrow stromal stem cells suggest a potential mechanism for bone fragility [J]. Cell Rep, 2019, 27(7): 2050-2062.
|
| [57] |
Bredella MA, Torriani M, Ghomi RH, et al. Vertebral bone marrow fat is positively associated with visceral fat and inversely associated with IGF-1 in obese women [J]. Obesity (Silver Spring), 2011, 19(1): 49-53.
|
| [58] |
Schwartz AV, Sigurdsson S, Hue TF, et al. Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults [J]. J Clin Endocrinol Metab, 2013, 98(6): 2294-2300.
|
| [59] |
Sheu Y, Amati F, Schwartz AV, et al. Vertebral bone marrow fat, bone mineral density and diabetes: The Osteoporotic Fractures in Men (MrOS) study [J]. Bone, 2017, 97: 299-305.
|
| [60] |
Usategui-Martin R, Perez-Castrillon JL, Briongos-Figuero L, et al. Genetic variants in obesity-related genes and the risk of osteoporotic fracture. The Hortega Follow-up Study [J]. Front Biosci (Landmark Ed), 2022, 27(1): 32.
|
| [61] |
Zhang Q, Riddle RC, Yang Q, et al. The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage [J]. Proc Natl Acad Sci U S A, 2019, 116(36): 17980-17989.
|