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中华肥胖与代谢病电子杂志

中华肥胖与代谢病电子杂志 ›› 2018, Vol. 04 ›› Issue (03) : 129 -135. doi: 10.3877/cma.j.issn.2095-9605.2018.03.002

所属专题： 文献；

论著

2型糖尿病患者腹臀脂肪与性别等因素的相关性研究
刘彦1, 吴波2, 曹雯3, 曹琳3, 胡咏新3, 陈国芳3, 茅晓东3, 刘超3,†()   
  1. 1. 225001　扬州，江苏省苏北人民医院内分泌科；210028　南京，南京中医药大学附属中西医结合医院内分泌分院，中国中医科学院江苏分院
    2. 210046　南京，南京中医药大学
    3. 210028　南京，南京中医药大学附属中西医结合医院内分泌分院，中国中医科学院江苏分院
  • 收稿日期:2018-07-07 出版日期:2018-08-30
  • 通信作者: 刘超

Correlation between android fat or gynoid fat percentage and multifactors including gender in patients with type 2 diabetes mellitus

Yan Liu1, Bo Wu2, Wen Cao3, Ling Cao3, Yongxin Hu3, Guofang Chen3, Xiaodong Mao3, Chao Liu3,†()   

  1. 1. Department of Endocrinology, Subei People’s Hospital of Jiangsu Province, Yangzhou 225001;Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
    2. Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028
    3. Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
  • Received:2018-07-07 Published:2018-08-30
  • Corresponding author: Chao Liu
  • About author:
    Corresponding author: Liu Chao, Email:
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引用本文：

刘彦, 吴波, 曹雯, 曹琳, 胡咏新, 陈国芳, 茅晓东, 刘超. 2型糖尿病患者腹臀脂肪与性别等因素的相关性研究[J]. 中华肥胖与代谢病电子杂志, 2018, 04(03): 129-135.

Yan Liu, Bo Wu, Wen Cao, Ling Cao, Yongxin Hu, Guofang Chen, Xiaodong Mao, Chao Liu. Correlation between android fat or gynoid fat percentage and multifactors including gender in patients with type 2 diabetes mellitus[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2018, 04(03): 129-135.

目的

探讨在南京某三甲医院内分泌科就诊行全身骨密度检查的2型糖尿病患者的腹部脂肪和臀部脂肪占比变化的规律和特点。

方法

回顾性分析从2013年3月到2016年3月江苏省中西医结合医院内分泌科门诊及病房就诊并行全身骨密度检查的内分泌代谢病患者，根据纳入标准，共纳入分析281例2型糖尿病患者的腹部内脏脂肪和臀部脂肪占比的相关数据，分别按性别、年龄、体质量指数进行分组分析。

结果

纳入的男性、女性患者的体质量指数无统计学差异；无论是腹部脂肪占比还是臀部脂肪占比女性患者均明显高于男性患者，且有统计学差异（P<0.001）。女性患者的腹部脂肪占比均随年龄增加而呈上升趋势，臀部脂肪占比均随年龄增加而呈下降趋势；女性患者在50~59.9岁腹部脂肪占比增加的速度最快；男性患者的腹部脂肪占比和臀部脂肪占比在70岁以下各年龄组保持相对稳定，在70岁以上均出现明显增长。男、女性腹部脂肪占比均随体质量指数增加而明显增加；在正常和超重体质量指数组，女性腹部脂肪占比和臀部脂肪占比均显著高于同体质量指数组的男性患者；在肥胖体质量指数组，男、女性患者的腹部脂肪占比无统计学差异，女性患者的臀部脂肪占比明显高于同体质量指数组的男性患者。

结论

2型糖尿病女性患者腹部脂肪占比和臀部脂肪占比总体均高于男性患者。围绝经期2型糖尿病女性患者的腹部脂肪占比增加最快，臀部脂肪占比下降最快，雌激素水平的变化可能伴随脂肪的重分布。

关键词: 全身骨密度检查, 腹部脂肪占比, 臀部脂肪占比, 体质量指数, 围绝经期
Objective

To investigate the regularity and characteristics of android and gynoid fat percentages in type 2 diabetes patients who underwent the whole body bone mineral density (BMD) examination in the Endocrinology Department of a tertiary general hospital in Nanjing.

Methods

Retrospective analysis of the clinic and ward patients of our department who received the whole body bone mineral density examination from Mar. 2013 to Mar. 2016 was performed. According to the inclusion criteria, the android fat percentage (AF%) and gynoid fat percentage (GF%) data of 281 cases was analyzed by gender groups, age groups and body mass index groups.

Results

BMI showed no difference between male and female groups. The AF% and GF% in female patients were significantly higher than those in male patients (P<0.001). The AF% increased with age while the GF% decreased with age in female patients. The AF% of female patients increased fastest between 50 and 69.9 years old. The AF% and GF% in male patients remained relatively stable in all age groups until 70 years old and the AF% and GF% in male patients increased significantly over 70 years old. The AF% increased significantly with the increase of BMI both in male and female patient groups. In the normal-weight and overweight group, AF% and GF% were significantly higher in female group than in male group. In the obesity group, there was no significant difference of AF% between men and women, but the GF% of female patients was significantly higher than that of male patients.

Conclusions

The AF% and GF% of female patients with type 2 diabetes mellitus was higher than those of male patients. Perimenopausal women had the fastest increase of AF% and the fastest decrease of GF%. Change of estrogen levels may be associated with the redistribution of adipose.

Key words: Whole body bone mineral density examination, android fat percentage, gynoid fat percentage, Bodymass index, Perimenopausal
表1 281例2型糖尿病患者不同性别分组测量资料
? 男性（n=118） 女性（n=163）
平均值 标准差 极值范围 平均值 标准差 极值范围
体重（kg）** 72.2 8.7 53.0-108.1 62.1 9.0 43.4-81.2
BMI（kg/m2） 24.7 2.8 19.0-37.4 24.6 3.3 17.2-33.7
AF%** 27.5 8.9 5.6-43.9 34.1 7.4 6.3-50.0
GF%** 3.1 2.0 0.1-9 4.7 3.8 0.1-28.8
图1 不同年龄组女性AF%变化图
图2 不同年龄组女性GF%变化图
表2 女性各年龄组测量资料
年龄（岁） n（人） AF% AF%范围 GF% GF%范围 BMI（kg/m2） BMI范围
20-39.9 13 28.09±7.47 15.90-41.60 9.08±4.07 3.00-14.90 23.22±2.98 18.40-29.00
40-49.9 17 28.24±8.50 6.30-43.00 7.34±2.57 2.4-11.20 23.22±3.18 18.80-29.00
50-59.9 54 34.9±5.36 19.30-46.80 4.16±3.10 10-12.10 25.06±3.16 18.50-33.70
60-69.9 51 34.80±8.18 11.80-50.00 4.13±4.32 .20-28.80 24.62±3.61 17.20-31.30
≥70 28 37.90±5.32 29.20-49.90 3.06±2.03 .20-7.30 25.27±3.37 19.90-32.40
图3 不同年龄组男性AF%变化图
图4 不同年龄组男性GF%变化图
表3 男性患者不同年龄组测量资料
年龄（岁） n（人） AF% AF%范围 GF% GF%范围 BMI(kg/m2) BMI范围
20-39.9 7 29.67±3.95 23.30-34.60 2.21±1.01 1.00-3.90 25.76±1.29 23.30-27.30
40-49.9 14 28.94±6.47 19.10-39.00 2.07±1.96 0.20-7.80 25.52±2.00 22.80-29.80
50-59.9 50 25.37±9.29 5.6-43.10 3.20±1.78 0.10-7.50 24.39±2.79 19.00-31.00
60-69.9 36 27.81±9.63 6.00-43.90 3.13±2.43 0.00-9.00 24.32±2.59 19.10-28.70
≥70 11 32.70±7.59 15.40-43.30 4.33±1.73 1.20-6.30 24.92±4.35 21.40-37.40
图5 男女性在不同BMI分组AF%的比较
图6 男女性在不同BMI分组GF%的比较
表4 男女不同BMI组的AF%和GF%测量
分组 男性（n=118） 女性（n=163）
n AF%（Χ±SD） AF%范围 GF%（Χ±SD） GF%范围 n AF%（Χ±SD） AF%范围 GF%（Χ±SD） GF%范围
BMI<25 kg/m2 57 22.37±8.78 5.6-37.7 3.22±2.07 .00-9.00 87 30.89±7.46 6.30-45.1 5.09±3.57 0.1-14.90
25 kg/m2 ≤BMI<30 kg/m2 58 32.19±6.04 19.6-43.9 2.96±2.06 .20-9.00 67 37.58±5.41 21.50-49.9 3.87±2.89 0.2-10.60
BMI ≥ 30 kg/m2 3 33.33±1.12 32.1-34.3 3.17±0.67 2.60-3.9 9 40.07±5.32 31.90-50 6.84±8.54 0.8-28.80
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