探讨微粒皮移植修复肥胖糖尿病下肢溃疡创面的临床疗效。

回顾性分析我院2014年1月至2020年1月诊治的34例肥胖糖尿病合并足部溃疡的患者，其中男21例，女13例；年龄61~74岁，采用伤口清创或联合负压吸引联合微皮粒部位进行修复，记录其溃疡创面面积和取皮面积、微粒皮扩展比，评估其愈合率和愈合速率，同时评估创面的愈合质量和瘢痕形成情况。

共34例患者创面面积平均为（42.7±31.2）cm²，取皮面积平均为（12.1±9.3）cm²，微粒皮扩展比为8:1~5:1，34例患者的一期平均愈合率为（92.3±4.7）%，联合VSD负压与未采用VSD负压吸引清创治疗愈合率和愈合速率对比差异无统计学意义，术后3个月的近期创面的愈合质量的总体优良达到97.1%；半年后随访瘢痕形成轻度共19例（55.9%），中度为11例（32.3%），重度为4例（11.8%）。

微粒皮移植修复肥胖糖尿病下肢溃疡创面具有愈合率高、愈合质量良好的特点，值得进一步推广应用。

To investigate the clinical effect of microskin transplantation in repairing obese diabetic lower limb ulcer wounds.

A retrospective analysis of 34 obese diabetic patients with foot ulcers diagnosed and treated in our hospital from 2014 to 2020, including 21 males and 13 females; aged 61-74 years old. Wound debridement with or without Vacuum Sealing Drainage (VSD) were used before microskin transplantation. The area of the ulcer wound, the area of the skin removed, and the expansion ratio of the micro-skin to evaluate the healing rate and healing rate were recorded, and the healing quality and scar formation of the wound also was evaluated.

The average wound area of 34 patients was (42.7±31.2) cm², the average skin area was (12.1±9.3) cm², and the microscopic skin expansion ratio was 8:1-5:1. The average primary healing rate of 34 patients was (92.3±4.7)%. There was no statistically significant difference in healing rate and healing rate between combined VSD negative pressure and non-VSD negative pressure suction debridement treatment. The overall excellent healing quality of the recent wounds at 3 months after surgery reached 97.1%; follow-up scars after half a year A total of 19 cases (55.9%) were mild, 11 cases (32.3%) were moderate, and 4 cases (11.8%) were severe.

Microskin transplantation to repair obese diabetic lower limb ulcer wounds has the characteristics of high healing rate and good healing quality, and it is worthy of further promotion and application.