切换至 "中华医学电子期刊资源库"

中华肥胖与代谢病电子杂志 ›› 2020, Vol. 06 ›› Issue (02) : 130 -134. doi: 10.3877/cma.j.issn.2095-9605.2020.02.011

所属专题: 文献

综述

肥胖与2型糖尿病关系的研究进展
赛米•赛麦提1, 买买提•依斯热依力2, 艾克拜尔•艾力3,()   
  1. 1. 830001 乌鲁木齐,新疆医科大学
    2. 新疆维吾尔自治区人民医院微创、疝和腹壁外科;新疆维吾尔自治区人民医院普外微创研究所
    3. 830001 乌鲁木齐,新疆医科大学;新疆维吾尔自治区人民医院微创、疝和腹壁外科;新疆维吾尔自治区人民医院普外微创研究所
  • 收稿日期:2019-05-04 出版日期:2020-05-30
  • 通信作者: 艾克拜尔?艾力
  • 基金资助:
    新疆维吾尔自治区引进高层次人才天池百人计划项目(201939)

Research progress of relationship between obesity and type 2 diabetes relations

Saimaiti Saimi•1, Yisireyili Maimaiti•2, Ali Aikebaier•3()   

  • Received:2019-05-04 Published:2020-05-30
  • Corresponding author: Ali Aikebaier?
引用本文:

赛米•赛麦提, 买买提•依斯热依力, 艾克拜尔•艾力. 肥胖与2型糖尿病关系的研究进展[J]. 中华肥胖与代谢病电子杂志, 2020, 06(02): 130-134.

Saimaiti Saimi•, Yisireyili Maimaiti•, Ali Aikebaier•. Research progress of relationship between obesity and type 2 diabetes relations[J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2020, 06(02): 130-134.

图1 肥胖与2型糖尿病的关系
[1]
Lancet T. Obesity and diabetes in 2017: a new year[J]. Lancet, 2017, 389(10064): 1.
[2]
Khunti S, Davies MJ, Khunti K. Clinical inertia in the management of type 2 diabetes mellitus: a focused literature review[J]. British Journal of Diabetes, 2015, 15(2): 65.
[3]
Hou X, Lu J, Weng J, Ji L, et al. Impact of waist circumference and body mass index on risk of cardiometabolic disorder and cardiovascular disease in Chinese adults: a national diabetes and metabolic disorders survey[J]. PloS one, 2013, 8(3): e57319.
[4]
Jourdan T, Godlewski G, Kunos G. Endocannabinoid regulation of β-cell functions: implications for glycaemic control and diabetes[J]. Diabetes Obesity & Metabolism,2016, 18(6): 549-557.
[5]
陈颖, 夏明锋, 李小英. 体脂分布与糖尿病风险[J]. 中国糖尿病杂志, 2017, 9(4): 218-220.
[6]
Gilleron J, Bouget G, Ivanov S, et al. Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance[J]. Cell reports, 2018, 25(12): 3329-3341.
[7]
Anna S, Jacob J, Baquero AF, et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss[J]. Journal of Clinical Investigation, 2014, 124(10): 4473-4488.
[8]
Bloemendaal LV, Veltman DJ, Kulve JST, et al. Brain Reward-System Activation in Response to Anticipation and Consumption of Palatable Food Is Altered by GLP-1 Receptor Activation in Humans (384-OR)[J]. Diabetes Obesity & Metabolism,2015, 17(9): 878-886.
[9]
Gribble FM, Reimann F. Function and mechanisms of enteroendocrine cells and gut hormones in metabolism[J]. Nature Reviews Endocrinology, 2019: 1.
[10]
Sharma D, Verma S, Vaidya S, et al. Recent updates on GLP-1 agonists: Current advancements & challenges[J]. Biomedicine & pharmacotherapy Biomedecine & pharmacotherapie, 2018, 108: 952-962.
[11]
Nauck MA, Meier JJ. The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions[J]. The lancet Diabetes & endocrinology, 2016, 4(6): 525-536.
[12]
Aso Y, Ozeki N, Terasawa T, et al. Serum level of soluble CD26/dipeptidyl peptidase-4 (DPP-4) predicts the response to sitagliptin, a DPP-4 inhibitor, in patients with type 2 diabetes controlled inadequately by metformin and/or sulfonylurea[J]. Translational Research, 2012, 159(1): 25-31.
[13]
Tanaka S, Kanazawa I, Notsu M, et al. Visceral fat obesity increases serum DPP-4 levels in men with type 2 diabetes mellitus[J]. Diabetes Research & Clinical Practice, 2016, 116: 1-6.
[14]
Sell H, Bluher M, Klöting N, et al. Adipose Dipeptidyl Peptidase-4 and Obesity[J]. Diabetes Care, 2013, 36(12): 4083-4090.
[15]
Ah LS, Young Ree K, Eun JY, et al. CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus[J]. Journal of Clinical Endocrinology & Metabolism,2013, 98(6): 2553-2561.
[16]
Sesti G, Avogaro A, Belcastro S, et al. Ten years of experience with DPP-4 inhibitors for the treatment of type 2 diabetes mellitus[J]. Acta diabetologica, 2019.
[17]
Daryabor G, Kabelitz D, Kalantar K. An update on immune dysregulation in obesity-related insulin resistance[J]. Scandinavian journal of immunology, 2019, 89(4): e12747.
[18]
Molofsky AB, Nussbaum JC, Hong-Erh L, et al. Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages[J]. Journal of Experimental Medicine, 2013, 210(3): 535-549.
[19]
Nijhuis J, Rensen SS, Slaats Y, et al. Neutrophil activation in morbid obesity, chronic activation of acute inflammation[J]. Obesity, 2012, 17(11): 2014-2018.
[20]
Saswata T, Young OD, Gautam B, et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase[J]. Nature Medicine, 2012, 18(9): 1407.
[21]
Li P, Liu S, Lu M, et al. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance[J]. Cell, 2016, 167(4): 973-984.e912.
[22]
Sud N, Zhang H, Pan K, et al. Aberrant expression of microRNA induced by high-fructose diet: implications in the pathogenesis of hyperlipidemia and hepatic insulin resistance[J]. Journal of Nutritional Biochemistry, 2017, 43: 125.
[23]
Lei W, Ning Z, Zun W, et al. MiR-499-5p Contributes to Hepatic Insulin Resistance by Suppressing PTEN[J]. Cellular Physiology & Biochemistry, 2015, 36(6): 2357-2365.
[24]
Lei W, Ning Z, Wang Z, et al. Pseudogene PTENP1 functions as a competing endogenous RNA (ceRNA) to regulate PTEN expression by sponging miR-499-5p[J]. Biochemistry, 2016, 81(7): 739-747.
[25]
Fengyun W, Yi Y, Dan J, et al. MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells[J]. Biochemical & Biophysical Research Communications, 2014, 445(2): 517-523.
[26]
Awazawa M, Gabel P, Tsaousidou E, et al. A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle[J]. Nature Medicine, 2017, 23(12): 1466-1473.
[27]
Madsbad S, Holst JJ. Guidelines: Surgical or medical therapy for patients with obesity and T2DM?[J]. Nature Reviews Endocrinology, 2016, 12(9): 500-502.
[28]
Westerveld D, Yang D. Through Thick and Thin: Identifying Barriers to Bariatric Surgery, Weight Loss Maintenance, and Tailoring Obesity Treatment for the Future[J]. Surgery Research and Practice,2016, 2016(3): 1-7.
[29]
张鹏, 郑成竹. 中国肥胖和2型糖尿病外科治疗指南解读[J]. 糖尿病天地(临床), 2016, 24(10): 18-20.
[30]
ASMBS Clinical Issues Committee. Updated position statement on sleeve gastrectomy as a bariatric procedure[J]. surgery for obesity & related diseases official journal of the american society for bariatric surgery, 2012, 8(3): e21-e26.
[31]
王存川, 董志勇. 精准肥胖外科[J/CD]. 中华肥胖与代谢病电子杂志, 2016, 2(1):1-6.
[1] 曹雯佳, 刘学兵, 罗安果, 钟释敏, 邓岚, 王玉琳, 李赵欢. 超声矢量血流成像对2型糖尿病患者颈动脉壁剪切应力的研究[J]. 中华医学超声杂志(电子版), 2024, 21(07): 709-717.
[2] 陈嘉婷, 杜美君, 石冰, 黄汉尧. 母体系统性疾病对新生儿唇腭裂发生的影响[J]. 中华口腔医学研究杂志(电子版), 2024, 18(04): 262-268.
[3] 孟令凯, 李大勇, 王宁, 王桂明, 张炳南, 李若彤, 潘立峰. 袖状胃切除术对肥胖伴2型糖尿病大鼠的作用及机制研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(06): 638-642.
[4] 李猛, 姜腊, 董磊, 吴情, 贾犇黎. 腹腔镜胃袖状切除术治疗肥胖合并2型糖尿病及脂肪胰的临床研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(05): 554-557.
[5] 吉顺富, 汤晓燕, 徐进. 腹腔镜近端胃癌根治术中拓展胃后间隙在肥胖患者中的应用研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 393-396.
[6] 杨波, 胡旭, 何金艳, 谢铭. 腹腔镜袖状胃切除术管胃固定研究现状[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 452-455.
[7] 何羽. 腔镜微创手术治疗分化型甲状腺癌的研究进展[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 456-458.
[8] 赵淑樱, 张聃. 腹腔镜胃癌外科治疗进展与发展趋势[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 459-462.
[9] 白正林, 高明, 孟增东. 肩关节置换术后假体周围感染的研究进展[J]. 中华肩肘外科电子杂志, 2024, 12(03): 271-276.
[10] 陆文琪, 赵艳茹, 李焕娣, 樊欣娜, 王佳, 李萍. 2型糖尿病患者血清SMAD2和SOX6表达及其与蛋白尿的关系[J]. 中华肾病研究电子杂志, 2024, 13(03): 145-151.
[11] 武继敏, 袁春雨, 王鲁佳, 陈伟霞, 李晓东, 马丽虹. 重复经颅磁刺激治疗脑卒中后中枢性疼痛的研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2024, 14(03): 182-186.
[12] 唐小久, 胡曼, 许必君, 肖亚. 肥胖合并胃食管反流病患者严重程度与其焦虑抑郁及营养状态的相关性研究[J]. 中华消化病与影像杂志(电子版), 2024, 14(04): 360-364.
[13] 王璇, 娜扎开提·尼加提, 雒洋洋, 蒋升. 皮肤晚期糖基化终末产物浓度与2型糖尿病微血管并发症的相关性[J]. 中华临床医师杂志(电子版), 2024, 18(05): 447-454.
[14] 王星, 陈园, 热孜万古丽·乌斯曼, 郭艳英. T2DM、Obesity、NASH、PCOS共同致病因素相关的分子机制[J]. 中华临床医师杂志(电子版), 2024, 18(05): 481-490.
[15] 孙秀芹, 高美娟, 张琼阁, 吕凯敏, 王宏宇. 京西地区无心血管病史2型糖尿病中老年人群患心血管疾病的危险因素分析[J]. 中华临床医师杂志(电子版), 2024, 18(03): 245-252.
阅读次数
全文


摘要