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中华肥胖与代谢病电子杂志 ›› 2020, Vol. 06 ›› Issue (02) : 130 -134. doi: 10.3877/cma.j.issn.2095-9605.2020.02.011

所属专题: 文献

综述

肥胖与2型糖尿病关系的研究进展
赛米•赛麦提1, 买买提•依斯热依力2, 艾克拜尔•艾力3,()   
  1. 1. 830001 乌鲁木齐,新疆医科大学
    2. 新疆维吾尔自治区人民医院微创、疝和腹壁外科;新疆维吾尔自治区人民医院普外微创研究所
    3. 830001 乌鲁木齐,新疆医科大学;新疆维吾尔自治区人民医院微创、疝和腹壁外科;新疆维吾尔自治区人民医院普外微创研究所
  • 收稿日期:2019-05-04 出版日期:2020-05-30
  • 通信作者: 艾克拜尔?艾力
  • 基金资助:
    新疆维吾尔自治区引进高层次人才天池百人计划项目(201939)

Research progress of relationship between obesity and type 2 diabetes relations

Saimaiti Saimi•1, Yisireyili Maimaiti•2, Ali Aikebaier•3()   

  • Received:2019-05-04 Published:2020-05-30
  • Corresponding author: Ali Aikebaier?
引用本文:

赛米•赛麦提, 买买提•依斯热依力, 艾克拜尔•艾力. 肥胖与2型糖尿病关系的研究进展[J/OL]. 中华肥胖与代谢病电子杂志, 2020, 06(02): 130-134.

Saimaiti Saimi•, Yisireyili Maimaiti•, Ali Aikebaier•. Research progress of relationship between obesity and type 2 diabetes relations[J/OL]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2020, 06(02): 130-134.

图1 肥胖与2型糖尿病的关系
[1]
Lancet T. Obesity and diabetes in 2017: a new year[J]. Lancet, 2017, 389(10064): 1.
[2]
Khunti S, Davies MJ, Khunti K. Clinical inertia in the management of type 2 diabetes mellitus: a focused literature review[J]. British Journal of Diabetes, 2015, 15(2): 65.
[3]
Hou X, Lu J, Weng J, Ji L, et al. Impact of waist circumference and body mass index on risk of cardiometabolic disorder and cardiovascular disease in Chinese adults: a national diabetes and metabolic disorders survey[J]. PloS one, 2013, 8(3): e57319.
[4]
Jourdan T, Godlewski G, Kunos G. Endocannabinoid regulation of β-cell functions: implications for glycaemic control and diabetes[J]. Diabetes Obesity & Metabolism,2016, 18(6): 549-557.
[5]
陈颖, 夏明锋, 李小英. 体脂分布与糖尿病风险[J]. 中国糖尿病杂志, 2017, 9(4): 218-220.
[6]
Gilleron J, Bouget G, Ivanov S, et al. Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance[J]. Cell reports, 2018, 25(12): 3329-3341.
[7]
Anna S, Jacob J, Baquero AF, et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss[J]. Journal of Clinical Investigation, 2014, 124(10): 4473-4488.
[8]
Bloemendaal LV, Veltman DJ, Kulve JST, et al. Brain Reward-System Activation in Response to Anticipation and Consumption of Palatable Food Is Altered by GLP-1 Receptor Activation in Humans (384-OR)[J]. Diabetes Obesity & Metabolism,2015, 17(9): 878-886.
[9]
Gribble FM, Reimann F. Function and mechanisms of enteroendocrine cells and gut hormones in metabolism[J]. Nature Reviews Endocrinology, 2019: 1.
[10]
Sharma D, Verma S, Vaidya S, et al. Recent updates on GLP-1 agonists: Current advancements & challenges[J]. Biomedicine & pharmacotherapy Biomedecine & pharmacotherapie, 2018, 108: 952-962.
[11]
Nauck MA, Meier JJ. The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions[J]. The lancet Diabetes & endocrinology, 2016, 4(6): 525-536.
[12]
Aso Y, Ozeki N, Terasawa T, et al. Serum level of soluble CD26/dipeptidyl peptidase-4 (DPP-4) predicts the response to sitagliptin, a DPP-4 inhibitor, in patients with type 2 diabetes controlled inadequately by metformin and/or sulfonylurea[J]. Translational Research, 2012, 159(1): 25-31.
[13]
Tanaka S, Kanazawa I, Notsu M, et al. Visceral fat obesity increases serum DPP-4 levels in men with type 2 diabetes mellitus[J]. Diabetes Research & Clinical Practice, 2016, 116: 1-6.
[14]
Sell H, Bluher M, Klöting N, et al. Adipose Dipeptidyl Peptidase-4 and Obesity[J]. Diabetes Care, 2013, 36(12): 4083-4090.
[15]
Ah LS, Young Ree K, Eun JY, et al. CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus[J]. Journal of Clinical Endocrinology & Metabolism,2013, 98(6): 2553-2561.
[16]
Sesti G, Avogaro A, Belcastro S, et al. Ten years of experience with DPP-4 inhibitors for the treatment of type 2 diabetes mellitus[J]. Acta diabetologica, 2019.
[17]
Daryabor G, Kabelitz D, Kalantar K. An update on immune dysregulation in obesity-related insulin resistance[J]. Scandinavian journal of immunology, 2019, 89(4): e12747.
[18]
Molofsky AB, Nussbaum JC, Hong-Erh L, et al. Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages[J]. Journal of Experimental Medicine, 2013, 210(3): 535-549.
[19]
Nijhuis J, Rensen SS, Slaats Y, et al. Neutrophil activation in morbid obesity, chronic activation of acute inflammation[J]. Obesity, 2012, 17(11): 2014-2018.
[20]
Saswata T, Young OD, Gautam B, et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase[J]. Nature Medicine, 2012, 18(9): 1407.
[21]
Li P, Liu S, Lu M, et al. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance[J]. Cell, 2016, 167(4): 973-984.e912.
[22]
Sud N, Zhang H, Pan K, et al. Aberrant expression of microRNA induced by high-fructose diet: implications in the pathogenesis of hyperlipidemia and hepatic insulin resistance[J]. Journal of Nutritional Biochemistry, 2017, 43: 125.
[23]
Lei W, Ning Z, Zun W, et al. MiR-499-5p Contributes to Hepatic Insulin Resistance by Suppressing PTEN[J]. Cellular Physiology & Biochemistry, 2015, 36(6): 2357-2365.
[24]
Lei W, Ning Z, Wang Z, et al. Pseudogene PTENP1 functions as a competing endogenous RNA (ceRNA) to regulate PTEN expression by sponging miR-499-5p[J]. Biochemistry, 2016, 81(7): 739-747.
[25]
Fengyun W, Yi Y, Dan J, et al. MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells[J]. Biochemical & Biophysical Research Communications, 2014, 445(2): 517-523.
[26]
Awazawa M, Gabel P, Tsaousidou E, et al. A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle[J]. Nature Medicine, 2017, 23(12): 1466-1473.
[27]
Madsbad S, Holst JJ. Guidelines: Surgical or medical therapy for patients with obesity and T2DM?[J]. Nature Reviews Endocrinology, 2016, 12(9): 500-502.
[28]
Westerveld D, Yang D. Through Thick and Thin: Identifying Barriers to Bariatric Surgery, Weight Loss Maintenance, and Tailoring Obesity Treatment for the Future[J]. Surgery Research and Practice,2016, 2016(3): 1-7.
[29]
张鹏, 郑成竹. 中国肥胖和2型糖尿病外科治疗指南解读[J]. 糖尿病天地(临床), 2016, 24(10): 18-20.
[30]
ASMBS Clinical Issues Committee. Updated position statement on sleeve gastrectomy as a bariatric procedure[J]. surgery for obesity & related diseases official journal of the american society for bariatric surgery, 2012, 8(3): e21-e26.
[31]
王存川, 董志勇. 精准肥胖外科[J/CD]. 中华肥胖与代谢病电子杂志, 2016, 2(1):1-6.
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